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Aims: The 6-min walk test (6MWT) is a widely accepted tool for evaluating exercise tolerance and physical capacity, and the 6-min walk distance (6MWD) is an established prognostic factor in patients with heart failure (HF). However, the prognostic implications of post-6MWT dyspnoea remain unknown. We aimed to investigate the prognostic value of Borg scores after the 6MWT in patients with HF.
Methods And Results: Patients hospitalized for HF who underwent the 6MWT before discharge were included. Post-test dyspnoea was assessed using the Borg scale. Patients were stratified into low and high Borg score groups based on the median Borg score. The primary outcome was 2-year mortality. Among 1185 patients analysed, the median Borg score was 12. The 6MWD was significantly shorter in the high Borg score group than in the low Borg score group. The 2-year mortality rate was 20.2%. In the Kaplan-Meier analysis, the high Borg score group demonstrated an association with 2-year mortality, which remained significant even after adjustment for conventional risk factors, including the 6MWD. Furthermore, the Borg scale provided significant net reclassification improvement to the conventional risk model incorporating 6MWD.
Conclusion: In hospitalized patients with HF, post-6MWT Borg scores were associated with 2-year mortality independent of the 6MWD, providing incremental prognostic value to the 6MWD. Even if patients are able to walk long distances for 6 min, it is essential to closely observe dyspnoea immediately thereafter.
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http://dx.doi.org/10.1093/eurjpc/zwae291 | DOI Listing |
Monaldi Arch Chest Dis
September 2025
Department of Pulmonary, Critical Care and Sleep Medicine, All India Institute of Medical Sciences, Bhubaneswar.
The six-minute walk test (6-MWT) assesses functional exercise capacity in interstitial lung disease (ILD), providing key prognostic and functional insights. Logistical challenges, such as space and time limitations, limit its clinical use. The one-minute sit-to-stand test (1-MSTST) has emerged as a practical, space- and time-efficient alternative reflecting similar functional capacity.
View Article and Find Full Text PDFScand J Med Sci Sports
September 2025
Inter-University Laboratory of Human Movement Sciences, LIBM, University Savoie Mont-Blanc, EA 7424, Chambéry, France.
Cognitive performance during cognitive-motor dual-task (CMDT) varies with exercise intensity. According to the inverted-U theory, low-to-moderate intensity enhances cognition, but this remains unexplored in trained individuals who may better sustain cognitive performance at high intensities due to improved prefrontal cortex (PFC) homeostasis. Additionally, how sustained attention influences neuromuscular fatigue during whole-body CMDT is unclear.
View Article and Find Full Text PDFBiomedicines
July 2025
Department of Biology, University of Naples Federico II, 80126 Naples, Italy.
Since the COVID-19 pandemic, managing acute infections in symptomatic individuals, regardless of vaccination status, has been widely debated and extensively studied. Even more concerning, however, is the impact of COVID-19 on pregnant women-especially its effects on fetuses and newborns. Several studies have documented complications in both expectant mothers and their infants following infection.
View Article and Find Full Text PDFCureus
July 2025
Department of Orthopaedics and Traumatology, Mater Dei Hospital Malta, Msida, MLT.
Displaced midshaft clavicle fractures in adults have traditionally been managed non-operatively; however, recent literature has challenged this approach, particularly in active populations. This systematic review aims to compare functional outcomes, union rates, complication profiles, and patient satisfaction between operative and non-operative management strategies. A comprehensive search of PubMed, Embase, and the Cochrane Library was conducted in February 2025, identifying 10 eligible studies published from 2015 onwards: eight randomized controlled trials and two prospective cohort studies.
View Article and Find Full Text PDFJ Pharm Bioallied Sci
July 2025
Department of Physiology, Government Erode Medical College, Perundurai, Erode, India.
Background: Type 2 diabetes mellitus (T2DM) is associated with reduced cardiopulmonary function, decreased aerobic capacity, and increased respiratory complications. Effective non-pharmacological interventions are essential to improve exercise tolerance and overall health in diabetic individuals.
Objective: To evaluate the effectiveness of intercostal stretching techniques combined with aerobic dance exercises on VO₂ max and chest tightness in male patients with type 2 diabetes mellitus.