Efficacy of Adaptive Servo-Ventilation in Worsening Heart Failure.

Despite advancements in heart failure (HF) therapies, managing symptoms and congestion remains challenging for some patients. Adaptive servo-ventilation (ASV) has been used in Japan to treat residual congestion in chronic HF, but its efficacy remains debated.This study is a subanalysis of the SAVIOR-L study, a multicenter prospective observational study in Japan evaluating ASV in worsening HF.

Validation of Automated Respiratory Event Scoring in Type 3 Home Sleep Apnea Testing.

Purpose: Home sleep apnea tests (HSATs) using polygraphy devices are becoming increasingly important for evaluating obstructive sleep apnea. Alice NightOne, a widely used polygraphy device, includes automatic scoring software; however, more reliable scoring results can be provided by incorporating advanced algorithmic systems like Somnolyzer. Despite this, the accuracy of automatic scoring of this polygraphy device using such applications has not been specifically investigated.

Relationship between heart rate variability and cancer management.

In patients with advanced cancer, the prevalence rate of cardiac autonomic neuropathy (CAN) is high, and the prognosis of patients with CAN is generally poor. Although mechanisms including inflammation, infection, metabolism, neurodegeneration, toxic processes, and cancer treatment have been proposed as etiologies of CAN in cancer patients, these mechanisms have not been completely elucidated, and their relationship has only been described indirectly. A study involving 127 cancer patients revealed that both the disease and its treatments can lead to a decrease in heart rate variability (HRV) indicating the autonomic imbalance.

Sarcopenia in heart failure: Comparison of prognostic value between the Asian working Group for Sarcopenia 2014 and 2019 criteria.

Aim: Sarcopenia is a prevalent comorbidity among older patients with heart failure. This study aimed to evaluate the differences between sarcopenia diagnosed using the Asian Working Group for Sarcopenia (AWGS) 2014 and 2019 criteria in older patients with heart failure.

Methods: This study is a post hoc sub-analysis of data from the FRAGILE-HF study, a prospective, multicenter, observational study.

Association of Cardiovascular-Kidney-Metabolic Overlap with Physical Function and Prognosis in Older Patients with Heart Failure: A Post-hoc Analysis of the FRAGILE-HF and SONIC-HF.

Aims: The prevalence and impact of cardiovascular, kidney, and metabolic (CKM) overlap on physical function and prognosis in older patients with heart failure (HF) remain unclear. This study aimed to assess the impact of overlapping CKM conditions on physical function and prognosis in older patients with HF.

Methods: This post-hoc analysis of the FRAGILE-HF (main cohort) and SONIC-HF (validation cohort), both prospective multicentre studies, included patients aged ≥65 years who were hospitalised for HF.

Effects of Worsening Renal Function and Changes in Blood Urea Nitrogen Level During Hospitalization on Clinical Outcome in Patients with Acute Decompensated Heart Failure.

Worsening renal function (WRF) during hospitalization for acute decompensated heart failure (ADHF) is associated with poor clinical outcomes. Data on the impact of WRF on clinical outcomes, considering blood urea nitrogen (BUN) level and its changes in patients with ADHF, are scarce. This study aimed to investigate the effects of BUN and its changes during hospitalization on the relationship between WRF during hospitalization and post-discharge clinical outcomes in patients with ADHF.

The Impact of Macronutrient Intake on Sleep Quality in Female Endurance Athletes: A Pilot Observational Cross-Sectional Study.

: Sleep is essential for athletes. However, the impact of dietary habits on sleep quality in female endurance athletes at risk for low energy availability (LEA) is underexplored. This was a pilot study to examine the correlation between dietary patterns and sleep quality in healthy female endurance athletes.

Lifestyle change during the COVID-19 pandemic in Japan: implications for continuous positive airway pressure adherence in obstructive sleep apnea patient.

Background: Coronavirus disease 2019 (COVID-19), a global pandemic, has greatly altered our daily lifestyle. Although there have been many reports on the association between COVID-19 and sleep disorders, none have examined this association with continuous positive airway pressure (CPAP) therapy control. Therefore, we aimed to elucidate the impact of lifestyle changes on CPAP users during the COVID-19 pandemic in Japan.

Serum Levels of Exocrine Pancreatic Enzymes in Patients with Acute Decompensated Heart Failure.

Background: Interactions between the heart and other organs have been a focus in acute decompensated heart failure (ADHF). However, the association between ADHF and pancreatic exocrine insufficiency (PEI), which may lead to malnutrition, remains unclear. We investigated the relationship between exocrine pancreatic enzymes and ADHF.

Relationship Between Serum Levels of Pancreatic Exocrine Enzymes on Admission and Long-Term Clinical Outcomes in Patients with Acute Decompensated Heart Failure.

: Heart failure (HF) can damage organs because of poor perfusion and/or congestion. The interactions between HF and other organs have recently been studied; however, data on the interaction between HF and pancreatic exocrine function, which may affect fat and protein absorption and malnutrition, are scarce. We previously showed that the serum levels of pancreatic exocrine enzymes, as suggestive of pancreatic exocrine function, were low and associated with malnutrition or congestion in hospitalized patients with acute decompensated HF (ADHF).

Association of pre-admission exercise habit with post-discharge outcomes for older patients with heart failure.

Aims: The benefits of exercise in patients with heart failure are well documented. However, to date, the association between exercise habits and prognosis is yet to be evaluated. In this study, we investigated the association between pre-hospital exercise habits and post-discharge prognosis in older adult patients with heart failure.

Prognostic values of proteinuria in patients with acute heart failure.

Background: Renal dysfunction is significantly associated with poor prognosis in patients with heart failure. However, the prognostic significance of proteinuria as a potential marker of an impaired glomerular filtration barrier in acute heart failure (AHF) remains unclear. We aimed to investigate the prognostic value of urinary protein/creatinine ratio (PCR) in patients with AHF.

Comparative analysis of heart rate variability indices from ballistocardiogram and electrocardiogram: a study on measurement agreement.

Ballistocardiogram (BCG) captures minute vibrations generated by heart movements. These vibrations are converted into heart rate variability (HRV) indices, allowing their unobtrusive monitoring over extended periods, while reducing the burden on patients or subjects. In this study, to evaluate the agreement between the HRV indices, we compared the HRV indices estimated from the BCG device with those obtained from the gold standard electrocardiogram (ECG).

Estimated protein intake and prognosis in hospitalised heart failure: A focus on patients with and without chronic kidney disease.

Background And Aims: In patients with heart failure (HF), differences in the association between estimated protein intake (PI) and prognosis in those with and without chronic kidney disease (CKD) remain to be clarified. This study aimed to investigate whether the prognostic effects of the estimated PI differ between patients with HF with and without CKD.

Methods: We included patients who required hospitalisation owing to worsening HF between 2015 and 2019 and assessed the estimated PI based on the adjusted Maroni formula using the body mass index and urinary urea nitrogen level.

Prognostic Value of Sarcopenia Definitions and Outcomes Consortium Criteria in Older Patients with Heart Failure.

Objectives: The Asian Working Group for Sarcopenia in 2019 (AWGS 2019) emphasized muscle mass measurements. In contrast, the Sarcopenia Definitions and Outcomes Consortium (SDOC) prioritizes functional strength and mobility. Therefore, this study aimed to compare the prognostic utility of the SDOC and AWGS 2019 criteria for all-cause mortality in older patients with heart failure.

Effect of Cereal Consumption (Frugra) on Autonomic Nervous System Function in Healthcare Workers Who Skip Breakfast.

In this study, we aimed to clarify the effects of breakfast intervention on autonomic nerve function in healthcare workers who skip breakfast. This cross-sectional, interventional study was conducted between January 2020 and December 2021. All participants were full-time healthcare workers who completed a self-administered questionnaire on fatigue and subjective symptoms and underwent noninvasive autonomic nerve function tests.

Clinical advantages of reduced expiratory positive airway pressure setting in adaptive servo-ventilation therapy.

The clinical ramifications of adaptive servo-ventilation (ASV) therapy have stirred debate within the medical community. Given the potential detrimental effect of elevated expiratory positive airway pressure (EPAP) on cardiac output, we hypothesized that relatively lower EPAP may be recommended for successful ASV therapy. In-hospital patients with congestive heart failure refractory to medical therapy were included in the prospective cohort study of ASV therapy on prognosis in repeatedly hospitalized patients with chronic heart failure: longitudinal observational study of effects on readmission and mortality (SAVIOR-L) study.