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Feature extraction of rolling element bearings (REB) under variable-speed conditions is always one of the hot and difficult points in the field of fault diagnosis. Based on the encoder signal with the advantages of low noise, and direct correlation with machine dynamics, an optimized Savitzky-Golay and adaptive spectrum editing are proposed for REB feature extraction under low-speed and variable-speed conditions. Firstly, the estimated features of the instantaneous angular speed (IAS) and interference components are studied. Secondly, based on the proposed multipoint mean ratio indicator and parametric decomposition structure, an adaptive SG filter is proposed to remove the speed trend component. Thirdly, an adaptive spectrum editing scheme with no transition band and low computational cost advantages is proposed to detect REB fault based on the combination of the cyclic dislocation scheme, the Gaussian function and the Pearson theory. Simulation and experiments are used to verify the effectiveness of the proposed scheme.
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http://dx.doi.org/10.1016/j.isatra.2024.07.034 | DOI Listing |
Int J Biol Macromol
September 2025
School of Ethnic Medicine, Chengdu University of Traditional Chinese Medicine, China. Electronic address:
Wound healing is often hindered by bacterial infection, oxidative stress, and bleeding. Traditional dressings cannot simultaneously regulate multiple microenvironments. To address the shortcomings of traditional dressings, this study constructed a dual-network photothermal responsive multifunctional hydrogel OBCTCu based on four natural ingredients, including Bletilla striata polysaccharide (BSP), chitosan (CS), tannic acid (TA), and Cu.
View Article and Find Full Text PDFVirol Sin
September 2025
State Key Laboratory of Virology and Biosafety, RNA Institute, College of Life Sciences and Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, 430072, China; Institute for Vaccine Research at Animal Bio-safety Level Ⅲ Laboratory, Wuhan University, Wuhan, 430071, China.
Since the outbreak of SARS-CoV-2 in late 2019, the cumulative number of confirmed cases worldwide has surpassed 778 million, and the number of deaths has exceeded 7 million, posing a significant threat to human life and health while inflicting enormous losses on the global economy. At the stage where sequential immunization is recommended, there is a pressing demand for mRNA vaccines that can be rapidly adapted to new sequences, are easy to industrialize, and exhibit high safety and effectiveness. We developed a lipid nanoparticle (LNP) system, designated as WNP, which facilitates essentially in situ expression at the injection site and results in lower levels of pro-inflammatory factors in the liver, thus enhancing its safety compared to liver-targeted alternatives.
View Article and Find Full Text PDFTree Physiol
September 2025
Linze Inland River Basin Research Station, State Key Laboratory of Ecological Safety and Sustainable Development in Arid Lands, Northwest Institute of Eco-Environment and Resources, Chinese Academy of Sciences, Lanzhou 730000, China.
Leaves constitute a vital bottleneck in whole-plant water transport, and their water strategies are key determinants of plant competition and productivity. Nonetheless, our knowledge of leaf water strategies predominantly stems from single perspectives (i.e.
View Article and Find Full Text PDFAdv Child Dev Behav
September 2025
University of South Carolina, Columbia, SC, USA; Carolina Autism and Neurodevelopment Research Center, Columbia, SC, USA.
Autism spectrum disorder (ASD) unfolds over the first two years of life through complex interactions among developmental systems. Attention and autonomic nervous system (ANS) regulation represent foundational processes critical for adaptive engagement with the environment. Disruptions in these systems during early infancy may initiate developmental cascades that contribute to core ASD features, including social-communication challenges and restricted and repetitive behaviors, as well as the vast heterogeneity found within ASD.
View Article and Find Full Text PDFClin Microbiol Infect
September 2025
Institut Pasteur, Université Paris Cité, Immunologie des Infections Fongiques, Paris, France; Laboratoire de Parasitologie-Mycologie, AP-HP, Hôpital Saint-Louis, Paris, France. Electronic address:
Background: Invasive aspergillosis (IA) remains a major cause of morbidity and mortality in immunocompromised individuals, with an expanding spectrum of at-risk populations, particularly in the intensive care settings. Despite advances in antifungal pharmacotherapy, treatment outcomes remain suboptimal, and the rise of antifungal resistance highlights the need for adjunctive therapy that leverage host immune mechanisms. The pathogenesis of IA is primarily driven by impaired or dysregulated immune responses to Aspergillus species, mainly Aspergillus fumigatus.
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