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Carbendazim and acetamidine are pesticides that widely used to control pests and diseases in oilseed rape. In this paper, a rapid, accurate and reliable method was proposed for the detection of carbendazim and acetamidine with SERS microfluidic chip technology. Ag-ps(Polystyrene microspheres) microsphere SERS substrate was prepared by spin coating and magnetron sputtering deposition of Ag. The enhancement factor of prepared SERS substrate was 2.4 × 10. The SERS detection working curves were well fitted and the linear parameters R were 0.987 and 0.994, respectively. The limit of detection was 0.01 mg/mL. The use of SERS microfluidic chip to detect carbendazim and acetamidine is expected to provide a way for the detection of pesticide residues in crops, which has broad application prospects in the field of food safety.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11269829 | PMC |
http://dx.doi.org/10.1016/j.heliyon.2024.e33647 | DOI Listing |
Metal nanoparticles (MNPs) have emerged as vital components in nanotechnology due to their unique ability to concentrate light at the nanoscale. This property makes them especially valuable in biosensing applications, where high sensitivity is essential. At the same time, cellulose-based materials like paper offer an affordable, widely available, and versatile platform, making them ideal for the development of paper-based microfluidic analytical devices (μPADs).
View Article and Find Full Text PDFColloids Surf B Biointerfaces
August 2025
European Laboratory for non-linear spectroscopy (LENS), Via Nello Carrara 1, Sesto Fiorentino, (FI) 50019, Italy; National Institute of Optics (INO), National Research Council, Via Nello Carrara 1, Sesto Fiorentino, (FI) 50019, Italy.
Multifunctional magneto-plasmonic nanoparticles (MP-NPs) are attracting increasing interest for biomedical applications due to their dual magnetic and optical properties. However, existing synthesis protocols for MP-NPs could be limited by harsh conditions or lengthy, complex procedures. These limitations can hinder the development of nanosystems that work effectively in biological dispersion.
View Article and Find Full Text PDFSmall
August 2025
State Key Laboratory of Chemical Safety, College of Control Science and Engineering, China University of Petroleum (East China), Qingdao, 266580, China.
This study presents the development of a novel highly efficient light-trapping 3D Au plasmonic cone-arrays-in-bowl (CAIB) surface-enhanced Raman scattering (SERS) platform. The innovative platform integrates a pump-free microfluidic device with a highly sensitive SERS detection system. The CAIB structures are fabricated using a combination of techniques, including polystyrene sphere self-assembly, inductively coupled plasma etching, and electron beam deposition.
View Article and Find Full Text PDFAnal Chem
August 2025
State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, P. R. China.
Studying the characteristics of T cell activation and cytokine secretion is crucial for understanding the cell-mediated immunological response (CMI). To assess this purpose, we present a droplet-based single-cell immunoassay platform, named Drop-SCIA, which uniquely integrates surface-enhanced Raman spectroscopy (SERS) with homogeneous-phase immunoassay, enabling highly sensitive, multiplexed cytokine detection at the single-cell level and offering superior target enrichment efficiency compared to the widely used interface-based ELISpot assay. Using this platform, we analyzed Jurkat T cell activation and further profiled IL-2 and IFN-γ secretion following coculture with normal breast epithelial cells (MCF-10A) and breast cancer subtypes (MCF-7, MDA-MB-231).
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
January 2026
School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China. Electronic address:
This study presents the development of a multifunctional microfluidic chip designed for the rapid detection and inactivation of hazardous bacterial contaminants in complex environmental and industrial settings. The chip integrates nanozyme cascade colorimetric reactions, surface-enhanced Raman spectroscopy (SERS), and photothermal sterilization, enabling multimodal bacterial detection and decontamination. Constructed using Au@Fe/ZIF nanomaterials, the platform exhibits robust glucose oxidase (GOx)-like and peroxidase (HRP)-like activities, facilitating quantitative bacterial analysis through enzyme cascade reactions and highly sensitive species identification via SERS.
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