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http://dx.doi.org/10.1007/s00216-024-05372-z | DOI Listing |
Adv Healthc Mater
September 2025
Institute for Complex Molecular Systems, Eindhoven University of Technology, Eindhoven, 5600 MB, the Netherlands.
Intestinal organoids are three-dimensional cellular structures that are cultured in laminin-rich Matrigel, yielding organoids with correct, basal-out polarity. Removal of Matrigel results in organoids with reversed, apical-out polarity, demonstrating its vital role. However, Matrigel's composition is ill-defined, and its pathogenic origin poses challenges in reproducibility.
View Article and Find Full Text PDFNat Commun
September 2025
Department of Chemical Engineering, University of Washington, Seattle, WA, 98195, USA.
Faraday Discuss
August 2025
Department of Chemistry, School of Natural Sciences, Joseph Banks Laboratories, Lincoln, LN6 7DL, UK.
Autocatalytic and/or self-replicating systems are important aspects of understanding the link between living systems (origins of life) and chemical networks. As a result, many scientists around the world are attempting to better understand these phenomena by producing chemical networks and linking them to self-assembly and pathway complexity (systems chemistry). We present here a superficially autocatalytic, self-replicating system that utilises dynamic imine chemistry coupled with self-assembling supramolecular hydrogelation kinetics driven by a nucleation autocatalytic cycle (autoinduction).
View Article and Find Full Text PDFChem Sci
August 2025
State Key Laboratory of Chemical Resource Engineering, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology Beijing 100029 P. R. China +86-10-64425385 +86-10-64412131.
[This corrects the article DOI: 10.1039/C5SC00994D.].
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