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Nanomechanical measurements, especially the detection of weak contact forces, play a vital role in many fields, such as material science, micromanipulation, and mechanobiology. However, it remains a challenging task to realize the measurement of ultraweak force levels as low as nanonewtons with a simple sensing configuration. In this work, an ultrasensitive all-fiber nanonewton force sensor structure based on a single-mode-tapered U-shape multimode-single-mode fiber probe is proposed and experimentally demonstrated with a limit of detection of ~5.4 nanonewtons. The use of the sensor is demonstrated by force measurement on a human hair sample to determine the spring constant of the hair. The results agree well with measurements using an atomic force microscope for the spring constant of the hair. Compared with other force sensors based on optical fiber in the literature, the proposed all-fiber force sensor provides a substantial advancement in the minimum detectable force possible, with the advantages of a simple configuration, ease of fabrication, and low cost.
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http://dx.doi.org/10.1126/sciadv.adk8357 | DOI Listing |
J Colloid Interface Sci
September 2025
State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China; Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beijing 100049, China.. Electronic address:
This study presents a straightforward and rapid method for preparing graphene aerogel by integrating a sodium alginate (SA)-metal ion crosslinking system, a bubble template, and an osmotic dehydration process. Graphene oxide (GO) nanosheets were dispersed into the solution crosslinked by SA and metal ions, leading to rapid gelation of GO under ambient conditions. To minimize structural damage to the porous network caused by water molecules during the drying process, an osmotic dehydration technique was employed as an auxiliary drying method.
View Article and Find Full Text PDFAdv Mater
September 2025
Faculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznańskiego 8, Poznań, 61-614, Poland.
AlN is a core material widely used as a substrate and heat sink in various electronic and optoelectronic devices. Introducing luminescent properties into intrinsic AIN opens new opportunities for next-generation intelligent sensors, self-powered displays, and wearable electronics. In this study, the first evidence is presented of AlN crystals exhibiting satisfactory mechanoluminescence (ML), photoluminescence (PL), and afterglow performance, demonstrating their potential as novel multifunctional optical sensors.
View Article and Find Full Text PDFJ Virol
September 2025
Laboratory of Ultrastructural Virology, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan.
Double-stranded RNA (dsRNA), which induces an innate immune response against viral infections, is rarely detected in influenza A virus (IAV)-infected cells. Nevertheless, we previously reported that the influenza A viral ribonucleoprotein (vRNP) complex generates looped dsRNAs during RNA synthesis . This finding suggests that IAV possesses a specific mechanism for sequestering dsRNA within infected cells, thereby enabling viral evasion of the innate immune response.
View Article and Find Full Text PDFCureus
August 2025
Department of Orthodontic Science, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, JPN.
Purpose Improved superelastic nickel-titanium (Ni-Ti) alloy wires (ISWs) can be used not only for aligning but also for closing the extraction space. The objective of this study was to measure and compare the force and moment generated during mandibular molar protraction using an ISW combined with either short or long hooks under simulated crowded dentition conditions. Materials and methods Assuming crowded dentition following mandibular first premolar extraction, we designed a three-tooth model simulating the canine, the second premolar, and the first molar.
View Article and Find Full Text PDFIEEE Internet Things J
August 2025
Geometric Media Lab, School of Arts, Media and Engineering and School of Electrical, Computer and Energy Engineering, Arizona State University, Tempe, AZ 85281 USA.
Human gait analysis with wearable sensors has been widely used in various applications, such as daily life healthcare, rehabilitation, physical therapy, and clinical diagnostics and monitoring. In particular, ground reaction force (GRF) provides critical information about how the body interacts with the ground during locomotion. Although instrumented treadmills have been widely used as the gold standard for measuring GRF during walking, their lack of portability and high cost make them impractical for many applications.
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