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This study aimed to assess the impact of light perception presence or absence on visual function recovery in patients with traumatic optic neuropathy (TON). A retrospective analysis was conducted on the clinical data of 206 TON patients. Based on the presence or absence of light perception after injury, patients were categorized into a light perception group and a non-light perception group. A comparison was made between the two groups regarding visual acuity recovery before and after treatment. The non-light perception group comprised 63 patients, with a treatment effectiveness rate of 39.68%. The light perception group consisted of 143 patients, with a treatment effectiveness rate of 74.83%. The difference between the two groups was statistically significant (χ = 23.464, P < 0.01). Subgroup analysis indicated that surgical treatment appeared to be more effective than steroid hormone therapy for patients with light perception. Conversely, for patients without light perception, there was no significant difference in the effectiveness of the two methods. The total effectiveness rate of the light perception group was significantly higher than that of the non-light perception group, suggesting that patients with light perception before treatment experience better outcomes compared to those without light perception. Treatment choices should be individualized to ensure optimal results.
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http://dx.doi.org/10.1038/s41598-024-54324-1 | DOI Listing |
Food Chem X
August 2025
College of Light Industry and Food Engineering, Guangxi University, Nanning, 530004, China.
This study utilized integrated sensory-guided, machine learning, and bioinformatics strategies identify umami-enhancing peptides from , investigated their mechanism of umami enhancement, and confirmed their umami-enhancing properties through sensory evaluations and electronic tongue. Three umami-enhancing peptides (APDGLPTGQ, SDDGFQ, and GLGDDL) demonstrated synergistic/additive effects by significantly enhancing umami intensity and duration in monosodium glutamate (MSG). Furthermore, molecular docking showed that these umami-enhancing peptides enhanced both the binding affinity and interaction forces between MSG and the T1R1/T1R3 receptor system, thereby enhancing umami perception.
View Article and Find Full Text PDFPsychophysiology
September 2025
Department of Cognitive Neurology, University Medical Center Göttingen, Göttingen, Germany.
Exercise influences visual processing and is accompanied by neural and physiological changes in the body. Yet, the underlying mechanisms by which neural and physiological responses to exercise impact ensuing perception remain poorly understood. In particular, the effects of exercise-induced cardiac changes on visual perception and electrophysiological activity are unclear.
View Article and Find Full Text PDFAccid Anal Prev
September 2025
Department of Traffic Engineering and Key Laboratory of Road and Traffic Engineering Ministry of Education, Tongji University, Shanghai 201804, China. Electronic address:
In future traffic environments dominated by highly autonomous vehicles (AVs), pedestrians may face challenges in accurately interpreting AV behavior, thereby potentially increasing the risk of pedestrian-AV interactions. External human-machine interfaces (eHMIs) have been proposed to facilitate communication between AVs and pedestrians; however, comprehensive evaluations using objective data from real-world interactions are limited. This study developed a systematic evaluation framework grounded in the ISO 9241-11 standard, integrating four key indicators: decision accuracy, comprehensibility, decision efficiency, and perceived safety.
View Article and Find Full Text PDFEur J Ophthalmol
September 2025
vEyes NPO, vEyes Lab, Milo, Italy.
PurposeTo introduce, describe and validate a novel, 3D-printed portable slit lamp system integrated with a macro lens-equipped smartphone, providing clinicians with a quick, easy, and effective method for obtaining high-quality clinical images.Materials and MethodsA 3D-printed portable slit lamp was developed, comprising a warm white LED light pen housed in a custom case with a biconvex lens focusing light through a 0.4 mm slit.
View Article and Find Full Text PDFJ Refract Surg
September 2025
From the Department of Ophthalmology at University of São Paulo, São Paulo, Brazil.
Purpose: To analyze stabilization results using various standard and accelerated corneal cross-linking (CXL) protocols in patients younger than 18 years.
Methods: This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) 2020 guidelines. A bibliographic search was carried out based on PubMed and Scopus data, with the last being performed in December 2024.