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http://dx.doi.org/10.26635/6965.6358 | DOI Listing |
Pediatr Radiol
September 2025
Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, No.1 Shuaifuyuan, Dongcheng District, Beijing, 100730, China.
Background: Hand-wrist radiographs may not fully reflect skeletal bone age (BA) during mid-to-late puberty. Knee magnetic resonance imaging (MRI), a non-radiative imaging technique, may provide detailed evaluation of the lower limbs.
Objective: To validate the San Diego MRI-based knee BA atlas in a Chinese adolescent cohort presenting with growth deceleration, evaluate the concordance between knee and hand-wrist BA, and explore factors influencing potential discrepancies.
Mol Carcinog
August 2025
Department of Surgical Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Papillary thyroid cancer (PTC) often presents as anatomically distinct foci in bilateral lobes. However, it remains controversial whether these foci arise independently from distinct malignant progenitor cells or result from the dissemination of the primary lesion. Fifteen pairs of bilateral PTC at Stage I were enrolled, and sequencing was performed using a 437-cancer-gene panel (Geneseeq).
View Article and Find Full Text PDFJ Clin Med
July 2025
Faculty of Biomedical Sciences, Universitàdella Svizzera Italiana (USI), 6900 Lugano, Switzerland.
: Oncocyte-rich indeterminate thyroid nodules (O-ITNs) present diagnostic and management challenges due to overlapping features between benign and malignant lesions and differing cytological classifications. This study aimed primarily to assess the ultrasound (US) characteristics and US-based risk of O-ITNs using the American College of Radiology Thyroid Imaging Reporting And Data Systems (ACR TI-RADS). A secondary objective was to compare the Bethesda System for Reporting Thyroid Cytopathology (BSRTC) and Italian Consensus for the Classification and Reporting of Thyroid Cytology (ICCRTC) cytological systems regarding classification and clinical management implications for O-ITNs.
View Article and Find Full Text PDFThyroid
July 2025
Department of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy.
Careful consideration of the differential diagnosis of discordant thyroid function tests (TFTs) is fundamental to prevent mismanagement, waste of resources, uncover rare thyroid disorders, or other underlying critical conditions in patients referred for the evaluation of this issue. Here, we describe the frequency of underlying diagnoses and focus on cases in which the identification of analytical interferences led to the discovery of lymphoproliferative disorders. This is a retrospective cross-sectional study including all consecutive patients referred to the Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano, for suspected central hyperthyroidism between January 2017 and February 2025.
View Article and Find Full Text PDFAm J Otolaryngol
August 2025
Division of Endocrine Head & Neck Surgery, Department of Otolaryngology, Head & Neck Surgery, Emory University, Atlanta, GA, USA.
Background/purpose: Clinicians involved in thyroid and parathyroid surgical care can harbor strongly held beliefs meant to achieve the best outcomes, sometimes based on erroneous or outdated evidence. This article will clarify some common practices that can be refuted by critical analysis of the literature.
Methods: Observations in clinical practice of the most strongly communicated practice patterns were compared to review of published literature.