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Owing to the proximity of the ear canal to the central nervous system, in-ear electrophysiological systems can be used to unobtrusively monitor brain states. Here, by taking advantage of the ear's exocrine sweat glands, we describe an in-ear integrated array of electrochemical and electrophysiological sensors placed on a flexible substrate surrounding a user-generic earphone for the simultaneous monitoring of lactate concentration and brain states via electroencephalography, electrooculography and electrodermal activity. In volunteers performing an acute bout of exercise, the device detected elevated lactate levels in sweat concurrently with the modulation of brain activity across all electroencephalography frequency bands. Simultaneous and continuous unobtrusive in-ear monitoring of metabolic biomarkers and brain electrophysiology may allow for the discovery of dynamic and synergetic interactions between brain and body biomarkers in real-world settings for long-term health monitoring or for the detection or monitoring of neurodegenerative diseases.
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http://dx.doi.org/10.1038/s41551-023-01095-1 | DOI Listing |
Microsyst Nanoeng
September 2025
School of Integrated Circuits and Electronics, Beijing Institute of Technology, Beijing, China.
Piezoelectric MEMS loudspeakers based on cantilever diaphragms have demonstrated promising electroacoustic efficiency and low-frequency sound pressure level (SPL). However, their total harmonic distortion (THD) significantly increases near the first resonant frequency, and high-frequency SPL (above 10 kHz) rapidly decreases due to the resonance frequency and bandwidth limitations, severely affecting sound quality. This work presents a piezoelectric MEMS loudspeaker featuring a 2.
View Article and Find Full Text PDFSci Rep
September 2025
VIE, Inc, Kanagawa, Japan.
Music-evoked nostalgia has the potential to assist in recalling autobiographical memories and enhancing well-being. However, nostalgic music preferences vary from person to person, presenting challenges for applying nostalgia-based music interventions in clinical settings, such as a non-pharmacological approach. To address these individual differences, we developed the Nostalgia Brain-Music Interface (N-BMI), a neurofeedback system that recommends nostalgic songs tailored to each individual.
View Article and Find Full Text PDFBMC Genomics
August 2025
Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, P. R. China.
Background: Kernel row number (KRN) and ear length (EL) are key traits that contributes greatly to grain yield in maize (Zea mays L.). Although some quantitative trait loci (QTL) for KRN or EL have been identified, few have been effectively utilized in breeding.
View Article and Find Full Text PDFAuris Nasus Larynx
August 2025
Department of Otolaryngology, Head and Neck Surgery, Ehime University School of Medicine, Ehime 791-0295, Japan.
Robotic and computer-assisted systems for ear surgery are receiving growing attention as tools to overcome the challenges intrinsic to the delicate, restricted operative field of the middle and inner ear. This review highlights recent advances in robotic platforms, clinical outcomes, and emerging technologies such as augmented reality (AR), virtual reality (VR), and artificial intelligence (AI). Multiple groups worldwide have introduced robotic devices that aid or automate tasks like mastoid drilling, stapes footplate fenestration, and cochlear implant (CI) electrode insertion.
View Article and Find Full Text PDFJ Public Health Manag Pract
July 2025
Author Affiliation: Ear Care Nepal, Star Hospital, Lalitpur, Nepal (Drs Maharjan and Rajbhandari).
Objective: The primary cause of hearing loss in Nepalese children is chronic otitis media. General lack of awareness about ear and hearing health, paired with usage of traditional malpractices to treat common ear problems, has contributed to an increased morbidity of chronic otitis media and consequent hearing loss. The aim is to evaluate the practices and awareness of ear and hearing health among female community health volunteers (FCHVs).
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