A complicated infection by cutaneous and pulmonary in a Chinese immunocompetent patient: a case report.

Front Cell Infect Microbiol

Department of Respiratory Medicine, National Key Clinical Specialty, Branch of National Clinical Research Center for Respiratory Disease, Xiangya Hospital, Central South University, Changsha, Hunan, China.

Published: September 2023


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Article Abstract

Nocardiosis is an infectious disease caused by that primarily affects immunocompromised hosts. is a common opportunistic pathogen that causes disease in humans, including pulmonary and extrapulmonary infection. spp. infection is uncommon, and infection with and is even rarer. A 59-year-old immunocompetent woman with risk factors for environmental exposure developed nocardiosis and presented to the hospital with a cough, shortness of breath, hemoptysis, and a back abscess. An enhanced computed tomography (CT) of the chest revealed partial destruction of the right lung, as well as consolidation of the right upper lobe. Rare pathogens and were detected by metagenomic next-generation sequencing (mNGS) from abscess on the back and lung puncture tissue, respectively. She was treated with a combination of antibiotics and was finally discharged with a good prognosis. In this case, we present a patient who was successfully diagnosed with and infection using mNGS. This importance of using mNGS in pathogen detection and the effective use of antibiotics in treating patients with long-term rare infections is highlighted in this report.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467026PMC
http://dx.doi.org/10.3389/fcimb.2023.1229298DOI Listing

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