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Herein, we report nanodiamond oxide (NDOx), obtained from modified Hummers' oxidation of nanodiamond (ND), showing excellent proton conductivity and thermal stability. NDOx possesses hydrophilicity resulting in higher water adsorption and the retention of functional groups at elevated temperatures can be attributed to the high proton conductivity and thermal stability, respectively.
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http://dx.doi.org/10.1039/d3cc02016a | DOI Listing |
Int J Pharm Pract
September 2025
Department of Pharmaceutical Care, Faculty of Pharmacy, Chiang Mai University, Suthep Road, Suthep, Mueang, Chiang Mai 50200, Thailand.
Objectives: Proton pump inhibitors (PPIs) are commonly used among these patients to prevent upper gastrointestinal bleeding (UGIB) in anticoagulated patients. However, their clinical benefits among patients receiving OACs with a history of UGIB remain inconclusive. This study aimed to summarize the clinical benefits of PPIs for the secondary prevention of recurrent UGIB among patients using OACs.
View Article and Find Full Text PDFChem Asian J
September 2025
School of Chemistry and Chemical Engineering, Hainan University, Haikou, 570228, China.
Molecules that exhibit excited-state intramolecular proton transfer (ESIPT) have demonstrated great promise in fluorescent probes. The electronic effect of substituents has an important influence on the ESIPT process. In this study, we investigated the effects of substituents on the ESIPT mechanism and the photophysical behavior of single-benzene fluorophore (SBF) derivatives with computational chemistry methods.
View Article and Find Full Text PDFChemistry
September 2025
National Engineering Research Center for Carbohydrate Synthesis, Jiangxi Normal University, Nanchang, 330022, China.
We report a glycosyl radical-based, 1,2-trans-selective synthesis of C-aryl glycosides of 2-deoxy-2-amino-sugars from glycals via photoredox PCET/Ni dual catalysis. Mechanistic studies indicate that glycosyl radical formation involves the generation of an N-radical through a proton-coupled electron transfer (PCET) process, followed by its addition to the glycal. This protocol features: a) the use of an inexpensive organic photosensitizer and readily available glycals and aryl bromides; b) good functional group tolerance for both aryl bromides and glycal substrates; c) excellent diastereoselectivity, with exclusive formation of the 1,2-trans C-glycosides in all cases.
View Article and Find Full Text PDFAcc Chem Res
September 2025
Division of Materials and Manufacturing Science, Graduate School of Engineering, The University of Osaka, 2-1 Yamada-oka, Suita, Osaka 565-0871, Japan.
ConspectusHydrogen spillover, the simultaneous diffusion of protons and electrons, has recently emerged as a key phenomenon in the functionalization of hydrogen in cutting-edge research fields. Its occurrence has been found to significantly impact hydrogen-related fields of science, such as catalysis, reduction, and hydrogen storage. Since the discovery of hydrogen spillover more than half a century ago, although many scientists have reported its unique properties and have attempted to utilize them, no practical advanced applications have been established yet.
View Article and Find Full Text PDFRadiother Oncol
September 2025
Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Northern Ireland, UK.
Introduction: Preclinical evidence has demonstrated the potential of FLASH radiotherapy (FLASH-RT) to spare normal tissues compared to conventional (CONV) exposures. Most FLASH studies have used ultra-high dose rate (>40 Gy/sec) electrons and protons whilst comparatively few studies have reported photon FLASH responses. Given the widespread use of photons clinically, there is a need to characterise the FLASH effect using photons.
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