Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Obesity-related complications (ORCs), such as type 2 diabetes (T2D) and cardiovascular disease, contribute considerably to the clinical and economic impacts of obesity. To obtain a holistic overview of health and weight management attempts for people with obesity in Europe, we designed the cross-sectional RESOURCE survey to collect data on comorbidities, healthcare resource use (HCRU) and weight loss strategies from people with obesity in France, Germany, Italy, Spain, Sweden and the UK.
Methods: Adults (≥18 years old) with self-reported body mass index (BMI) ≥30 kg/m who reported interacting with primary or secondary healthcare services in the past 12 months, but had not been pregnant during this time, were recruited from an existing consumer research panel. All data were self-reported via an online survey (May-June 2021). Weight changes over the past year were calculated from participants' estimated weights.
Results: Of the 1850 participants in the survey, 26.3% reported that they had ≥3 ORCs from a set of 15 conditions of interest. The most frequently reported ORCs were hypertension (39.3% of participants), dyslipidaemia (22.8%) and T2D (17.5%). Participants in obesity class III (BMI 40 to <70 kg/m) were more likely to report multiple ORCs than those in lower obesity classes. The presence of multiple ORCs was linked to various types of HCRU, including a significantly increased chance of reporting hospitalization in the past year. Most participants (78.6%) had attempted to lose weight in the past year, but of those who also reported estimated weight changes, 73.4% had not experienced clinically meaningful weight loss of ≥5%.
Conclusions: ORCs are common in people with obesity, and are linked to increased HCRU. Together with the low reported success rate of weight loss attempts, this highlights an unmet need in Europe for enhanced weight management support for people with obesity.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359184 | PMC |
| http://dx.doi.org/10.1038/s41366-023-01325-1 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Incretin-Based Adjunct to Background Insulin Treatment for Managing Body Weight Excess in Type 1 Diabetes: An Expert Opinion Viewpoint From the Italian Association of Clinical Endocrinologists.
Diabetes Metab Res Rev
September 2025
Interdisciplinary Department of Medicine, School of Medicine, University of Bari 'Aldo Moro', Bari, Italy.
Overweight and obesity represent common chronic metabolic disorders in the general population, and observed trends describe a substantial growth in the prevalence of weight excess also among individuals with type 1 diabetes (T1D), the so-called 'lean phenotype' of diabetes. The sharp rise of weight excess and obesity-related cardio-nephron-metabolic burdens observed in T2D is expected to produce similar consequences in T1D, leading to the urgent need to endorse therapeutic protocols as in most parts of the World no adjunctive treatments are approved for T1D, making weight excess management challenging in these individuals. The notable results shown by newer glucagon-like peptide 1 receptor agonists (GLP-1RAs) and emerging dual agonists, especially while managing cardio-metabolic burdens, in T2D have encouraged fervent anecdotal and non-anecdotal research also in T1D, indicating that non-insulin injective agents can be effective and safe.
View Article and Find Full Text PDFFlavonoids in Tratt Fermentation Broth Ameliorate Obesity via DNMT3a/SIRT1-Mediated Epigenetic Modulation.
Food Sci Nutr
September 2025
School of Public Health, The Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education Guizhou Medical University Guiyang China.
Obesity-related complications are often driven by chronic inflammation and oxidative stress, exacerbated by aberrant DNA methylation. Natural products with anti-inflammatory and antioxidant properties may offer therapeutic potential. This study investigated the potential molecular mechanisms underlying the effects of Tratt fermentation broth (RRTFB) on obesity through targeted methylation, while also examining its primary active components and assessing its potential therapeutic value.
View Article and Find Full Text PDFFrom obesity to comorbidities: A comprehensive care approach for improved health by the Spanish Society of Internal Medicine.
Rev Clin Esp (Barc)
September 2025
Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Córdoba, Spain; Catedrático de Medicina, Universidad de Córdoba, Córdoba, Spain; Servicio de Medicina Interna, Hospital Universitario Reina Sofía, Córdoba.
Obesity is currently recognized as a chronic, progressive, and relapsing disease, and constitutes a major global public health challenge. This document, promoted by the Spanish Society of Internal Medicine through its Working Group on Diabetes, Obesity, and Nutrition, outlines a comprehensive, multidisciplinary approach to care, with a specific focus on obesity-related comorbidities. Excess adipose tissue is conceptualized as a systemic pathogenic agent that actively contributes to the pathophysiology of numerous complications, including cardiovascular disease, heart failure, chronic kidney disease, osteoarthritis, obstructive sleep apnea, and metabolic dysfunction-associated steatotic liver disease (MASLD).
View Article and Find Full Text PDFPatient-Reported Outcomes and Body Composition Changes in Patients With Colorectal Cancer During Chemotherapy: A Longitudinal Study.
J Nurs Manag
September 2025
School of Nursing, Fujian Medical University, Fuzhou 350005, Fujian, China.
To investigate the changes in self-reported outcomes and body composition among colorectal cancer (CRC) patients over the course of chemotherapy and differences in body composition among different self-reported trajectory subgroups. Prospective longitudinal study. This longitudinal study surveyed 201 CRC patients from a cancer hospital in Fuzhou, China.
View Article and Find Full Text PDFIdentification of subtypes of type 2 diabetes in the Chinese population and their distinct complication risk profiles.
Diabetes Obes Metab
September 2025
School of Public Health, and the Key Laboratory of Public Health Safety of Ministry of Education, Fudan University, Shanghai, China.
Aims: To identify and validate subgroups of type 2 diabetes in Chinese populations using clustering analysis and assess their complication risks.
Materials And Methods: Data from 5653 type 2 diabetes patients in the Shanghai Suburban Adult Cohort and Biobank (SSACB) and 6384 in the Southwest China Diabetic Chronic Complications Study were integrated. Using body mass index, fasting blood glucose, age at diabetes diagnosis, and triglycerides to high-density lipoprotein cholesterol ratio, k-means clustering was performed by sex in SSACB and validated in Southwest China Diabetic Chronic Complications Study.