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Background: Prevalence of obesity in Native American (NA) children is disproportionately high, indicating a higher risk of health disparities. Many children attend early care and education (ECE) programs, presenting an opportune environment to improve meal and menu quality as the intake of healthy foods is associated with lowered risk of childhood obesity.
Objectives: We aimed to examine the effectiveness of food service staff training on meals and menu quality across NA ECEs.
Methods: Food service staff from 9 participating ECE programs attended a 3-h training focused on Child and Adult Care Food Program (CACFP) best practices, and received a tailored, best-practice menu, and healthy recipes. Meals and menus prepared across 1 wk were examined per CACFP serving size assumptions at baseline, 4 mos, 6 mos, and 12 mos for all 9 programs. Healthy Eating Index (HEI), CACFP requirements and best practices achievement, and food substitutions quality (classified into superior, equivalent, and inferior based on the nutritional quality) were calculated. A repeated measures ANOVA model was used to determine the differences across time points.
Results: The total meal HEI score increased significantly from baseline to 4 mos (71.1 ± 2.1; 78.6 ± 5.0; = 0.004), but did not differ from baseline to 12 mos. Menu CACFP requirements and best practices achievement did not differ across time points, although achievement with CACFP requirements was already high at baseline. Superior nutrition quality substitutions declined from baseline to 6 mos (32.4 ± 8.9; 19.5 ± 10.9; = 0.007); however, it did not differ from baseline to 12 mos. Equivalent and inferior quality substitutions did not differ across time points.
Conclusions: Implementing a best-practice menu with healthy recipes showed immediate improvements in meal quality. Although the change did not sustain, this study showed evidence of an opportunity to educate and train food service staff. Robust efforts are needed for improving both meals and menus.This trial was registered ClinicalTrials.gov as NCT03251950 (https://clinicaltrials.gov/ct2/show/NCT03251950?cond=food+resource+equity&draw=2&rank=1).
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http://dx.doi.org/10.1016/j.cdnut.2023.100040 | DOI Listing |
ESMO Open
September 2025
Hospital del Mar Research Institute Barcelona, Medical Oncology Department, Hospital del Mar, Barcelona, Spain; Universitat Pompeu Fabra, Barcelona, Spain; Centro de Investigación Biomédica en Red de Oncología (CIBERONC-ISCIII), Madrid, Spain. Electronic address:
Background: Circulating tumor DNA (ctDNA) variations predict tumor response to systemic treatment (so-called molecular response) earlier than radiological assessment. However, a standardized categorization of molecular response is an unmet clinical need. Liquid biopsy-RECIST (LB-RECIST), based on aggregate variant allele frequency (aggVAF; sum of all detected variant allele frequencies in a sample) variations, has been proposed to stratify molecular response.
View Article and Find Full Text PDFCan Urol Assoc J
August 2025
Urologic Oncology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.
Introduction: Approximately 25% of patients diagnosed with bladder cancer have muscle-invasive disease (MIBC). While real-world data have highlighted opportunities to improve curative-intent treatment rates, comprehensive population-level data in Canada are limited. This study aimed to assess patterns of care and outcomes in a real-world cohort of MIBC in Canada.
View Article and Find Full Text PDFFront Immunol
August 2025
College of Public Health, Zhengzhou University, Zhengzhou, China.
Background: extensive-stage small cell lung cancer (ES-SCLC) were the majority of SCLC patients. Recently the combination of chemotherapy with immune checkpoint inhibitors (ICIs) have emerged as the new first-line treatment standard for ES-SCLC. However, the specific patient populations that are most likely to benefit from this treatment remains to be clearly identified making the establishment of baseline biomarkers critical.
View Article and Find Full Text PDFFront Neurol
August 2025
China National College of Martial Arts, Beijing Sports University, Beijing, China.
Background: This study aims to evaluate the effects of remote Baduanjin Qigong intervention on the quality of life and physical function in patients with mild to moderate Parkinson's disease (PD) through a randomized controlled trial (RCT) and to compare its efficacy with conventional exercise rehabilitation.
Methods/design: This RCT will enroll participants who, following baseline assessments and physical function tests, will be randomly allocated into one of three groups: the Qigong group (QG), the conventional exercise rehabilitation group (EG), or the control group (CG). The QG will engage in live-streamed Baduanjin (Eight-Section Brocade) sessions three times per week, each lasting 40 min, with additional self-practice encouraged.
Ther Adv Med Oncol
August 2025
Department of Clinical Oncology, Maria Sklodowska-Curie National Research Institute of Oncology, Kraków Branch, Kraków, Poland.
Background: Body mass index (BMI) and weight change are commonly explored as prognostic factors in breast cancer. However, their impact on outcomes with sacituzumab govitecan (SG) in metastatic triple-negative breast cancer (mTNBC) remains poorly defined.
Objectives: To evaluate the association between baseline BMI, weight change during treatment, and clinical outcomes-including survival and adverse events (AEs)-in a real-world Polish cohort of women with mTNBC receiving SG therapy.