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http://dx.doi.org/10.1158/1078-0432.CCR-22-3568 | DOI Listing |
Front Mol Biosci
August 2025
Department of Otolaryngology, Head and Neck Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Introduction: Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by stromal edema, albumin deposition, and pseudocyst formation. Anoikis, a process in which cells detach from the correct extracellular matrix, disrupts integrin junctions, thereby inhibiting improperly proliferating cells from growing or adhering to an inappropriate matrix. Although anoikis is implicated in immune regulation and CRSwNP pathogenesis, its specific mechanistic role remains poorly defined.
View Article and Find Full Text PDFWorld J Surg Oncol
August 2025
Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
Medicina (Kaunas)
August 2025
Pathophysiology Department, "George Emil Palade" University of Medicine, Pharmacy, Sciences and Technology of Targu Mures, 540142 Targu Mures, Romania.
: Spitz tumors represent a diagnostic challenge in dermatopathology due to their large spectrum of morphological characteristics and overlap with malignant lesions, especially in pathology departments where molecular pathology is not available. Even though most Spitz lesions are benign, the uncertainty around their biological behavior necessitates an integrated approach in daily practice. The objective of our study was to evaluate the epidemiological, macroscopic, and histopathological characteristics of Spitz lesions in accordance with .
View Article and Find Full Text PDFInt J Mol Sci
August 2025
Department of Pathology, Affiliated Chenggong Hospital, Xiamen University, Xiamen 361000, China.
In the original publication [...
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