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Article Abstract
is a significant source of phenolics. Owing to the incessant demand of green extraction procedures for phenolics from , ultrasound-assisted extraction (UAE) using deep eutectic solvents (DESs) was optimized. Among the tested DESs, betaine-levulinic acid afforded the highest total phenolic content (TPC). Moreover, the optimal extraction conditions elucidated from single-factor and response surface methodologies comprised a 52.41°C ultrasonic temperature, 46.48% water content of DES, and 26.99 ml/g liquid-to-solid ratio. The corresponding TPC (56.27 mg GAE/100 g DW) and antioxidant ability fitted the predicted values. UAE afforded superior TPC and antioxidant abilities with DESs than with traditional solvents. Using UHPLC-MS, seven phenolic acids, 18 flavonoids, and two bromophenols were identified and quantified. DES-UAE afforded the highest phenolic compound number (26) and sum of contents. These results disclose the high extraction efficiency of DES-UAE for phenolics and provide a basis for the higher-value application of this species.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712969 | PMC |
| http://dx.doi.org/10.3389/fnut.2022.1036436 | DOI Listing |
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