98%
921
2 minutes
20
Galangal is rich in flavonoids and polysaccharides but underutilized. In this study, galangal flavonoids and polysaccharides (GP-HN and GP-UN) were obtained by segmented extraction, used for chemical composition determination/structural characterization, and constructed for the emulsion delivery system. The results showed that galangin accounted for 71.45 % of total flavonoids. GP-HN and GP-UN were prepared by enzymatic-assisted high-temperature and ultrasonic extraction, which were low-molecular-weight pectin-type polysaccharides mainly constructed by galacturonic acid, galactose, and arabinose. GP-UN was the best emulsifier due to interfacial activities, emulsifying properties, interfacial resistance to bile salts displacement abilities, and anti-lipid digestion abilities of GPs. GP-UN emulsion could stably deliver flavonoids. This study presented a method for orderly reorganizing flavonoids and polysaccharides, guiding for utilization of whole bioactive components in galangal.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.ijbiomac.2022.09.051 | DOI Listing |
Biol Pharm Bull
September 2025
Department of Intensive Care Unit, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310007, China.
Ferroptosis is involved in the progression of sepsis-induced acute lung injury (ALI). Kaempferol is a flavonoid compound that can protect against ALI. 5-Methylcytosine (m5C) is involved in the pathogenesis of sepsis.
View Article and Find Full Text PDFFood Res Int
November 2025
State Key Laboratory of Marine Food Processing and Safety Control, Dalian Polytechnic University, Dalian 116034, Liaoning, China; Academy of Food Interdisciplinary Science, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, Liaoning, China; National Engineering Rese
Anthocyanins (AC) are natural bioactive substances with the excellent antioxidant properties, but its structure is susceptible to the external environmental factors with inevitably decreased bioavailability. In this work, γ-cyclodextrin based metal-organic framework (CD-MOF) shows high encapsulation efficiency (96.09 %) and satisfiable loading amount (24.
View Article and Find Full Text PDFCarbohydr Polym
November 2025
Shenzhen Key Laboratory of Food Nutrition and Health, College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen 518060, PR China. Electronic address:
Oral delivery of natural antioxidants represents a promising therapeutic strategy for ulcerative colitis (UC), yet their therapeutic efficacy is hindered by instability and poor accumulation at inflamed sites. To address this, we developed Galectin-3 (Gal-3)-targeted nanoparticles (ZDP-NPs) by encapsulating diosmetin within zein complexes modified with a galactose- and rhamnogalacturonan-I (RG-I)-rich pectin (PMTP, Mw: 228.8 kDa, DM: 34.
View Article and Find Full Text PDFMol Biol Rep
September 2025
Department of Biotechnology, Daegu University, Gyeongsan, 38453, Republic of Korea.
Background: Bacterial pathogen-associated molecular patterns (PAMPs), specifically lipopolysaccharide (LPS) from Gram-negative bacteria (E. coli, P. aeruginosa) and lipoteichoic acid (LTA) from Gram-positive bacteria (S.
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
Department of Physics, Indiana University Purdue University Indianapolis (IUPUI), Indianapolis, IN 46202, USA.
Conventional TiO₂ nanoparticle syntheses rely on high temperatures, toxic reagents and multi-step routes that impede scalability and sustainability. Here, we deliver the first green synthesis of TiO₂ nanoparticles (TiO₂ NPs) using polysaccharide- (42 mg GE g) and phenolic-rich (78 mg GAE g) Pinus patula leaf extract. GC-MS and LC-MS fingerprinting identify terpenoids, flavonoids and phenolic glycosides acting as simultaneous reducing, capping and stabilizing agents.
View Article and Find Full Text PDF