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Aggression among adolescents is a significant public health concern worldwide. To safeguard adolescents' physical and mental health, controlling the incidence of aggressive behavior and its triggers and drivers is necessary. Different risk factors in each environment drive adolescent aggression. These factors are interconnected, making the environment an ecosystem of aggression. This study aims to analyze the factors that influence adolescents' aggressive behavior and provide a basis for formulating measures to reduce such behavior in the future. This multicenter cross-sectional study was conducted in five middle schools in Lingbao City. The participants were junior high school students aged 11-15 years. Data were analyzed from January to March 2020 using the decision tree analysis method. The aggressive behavior scale, adolescent emotion regulation scale, family intimacy and adaptation scale, parental education participation scale, and a simple parenting style questionnaire were used for the investigation. Of the 581 participants, 25.5% demonstrated a tendency for aggressive behavior, while the remaining did not. The decision tree analysis showed that the incidence of adolescent aggression was the highest (54.8%) when the maternal overprotective score was greater than or equal to 17, the adolescent had low emotional control, and the mother's intelligence score was higher than 30. The decision tree model reflects the influencing factors of adolescent aggressive behavior from multiple levels and provides a reference for formulating effective intervention measures to control such behavior and its influencing factors.
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http://dx.doi.org/10.1080/00221325.2022.2094213 | DOI Listing |
Mater Today Bio
October 2025
School of Pharmacy, Henan Medical University, Xinxiang, Henan, China.
Breast cancer continues to present a major clinical hurdle, largely attributable to its aggressive metastatic behavior and the suboptimal efficacy of standard chemotherapeutic regimens. Cisplatin (CDDP) is a representative platinum drug in the treatment of breast cancer, however, its therapeutic application is often constrained by systemic toxicity and the frequent onset of chemoresistance. Here, we introduce a novel charge-adaptive nanoprodrug system, referred to as PP@, engineered to respond to tumor-specific conditions.
View Article and Find Full Text PDFAlpha Psychiatry
August 2025
The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, University of Electronic Science and Technology of China, 610036 Chengdu, Sichuan, China.
Objective: Physical aggression in schizophrenia patients carries significant societal implications. Previous studies on aggression prediction have primarily focused on hospitalized patients, overlooking specific rural community contexts in China. This study investigated multidimensional predictive factors to develop and validate a predictive model for predicting physical aggression in schizophrenia patients in rural communities in southwestern China.
View Article and Find Full Text PDFDev Psychopathol
September 2025
University of Vermont, Burlington, VT, USA.
Although depression can be transmitted across generations, less is known about how this cycle can be interrupted. This study examines whether the multilevel Fast Track intervention (clinicaltrials.gov, NCT01653535) disrupts intergenerational transmission of depression.
View Article and Find Full Text PDFDev Psychopathol
September 2025
Faculty of Behavioral and Social Sciences, Department of Pedagogy and Educational Sciences, University of Groningen, Groningen, the Netherlands.
Despite the growing body of research on the intergenerational transmission of problem behavior, there is a need for more integrative approaches that consider the interplay between genetic and environmental factors. This study uses unique longitudinal data from TRAILS (analytic sample = 2202), a prospective multiple-generation cohort study in the Netherlands to examine whether parents' problem behavior (parents' self-reported lifetime antisocial behavior and substance use, reported at mean age 40 years) predicts offspring problem behavior nearly two decades later (offspring self-reported aggression and delinquency at mean ages 29 and 32 years). In path analyses, independent and relative contributions of genetic (polygenic scores of parents and offspring) and environmental (harsh parenting) pathways were tested.
View Article and Find Full Text PDFAccid Anal Prev
September 2025
Department of Traffic Engineering and Key Laboratory of Road and Traffic Engineering Ministry of Education, Tongji University, Shanghai 201804, China. Electronic address:
In future traffic environments dominated by highly autonomous vehicles (AVs), pedestrians may face challenges in accurately interpreting AV behavior, thereby potentially increasing the risk of pedestrian-AV interactions. External human-machine interfaces (eHMIs) have been proposed to facilitate communication between AVs and pedestrians; however, comprehensive evaluations using objective data from real-world interactions are limited. This study developed a systematic evaluation framework grounded in the ISO 9241-11 standard, integrating four key indicators: decision accuracy, comprehensibility, decision efficiency, and perceived safety.
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