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The SARS-CoV-2 virus causes a respiratory disease in humans, known as COVID-19. The confirmatory diagnostic of this disease occurs through the real-time reverse transcription and polymerase chain reaction test (RT-qPCR). However, the period of obtaining the results limits the application of the mass test. Thus, chest X-ray computed tomography (CT) images are analyzed to help diagnose the disease. However, during an outbreak of a disease that causes respiratory problems, radiologists may be overwhelmed with analyzing medical images. In the literature, some studies used feature extraction techniques based on CNNs, with classification models to identify COVID-19 and non-COVID-19. This work compare the performance of applying pre-trained CNNs in conjunction with classification methods based on machine learning algorithms. The main objective is to analyze the impact of the features extracted by CNNs, in the construction of models to classify COVID-19 and non-COVID-19. A SARS-CoV-2 CT data-set is used in experimental tests. The CNNs implemented are visual geometry group (VGG-16 and VGG-19), inception V3 (IV3), and EfficientNet-B0 (EB0). The classification methods were k-nearest neighbor (KNN), support vector machine (SVM), and explainable deep neural networks (xDNN). In the experiments, the best results were obtained by the EfficientNet model used to extract data and the SVM with an RBF kernel. This approach achieved an average performance of 0.9856 in the precision macro, 0.9853 in the sensitivity macro, 0.9853 in the specificity macro, and 0.9853 in the F1 score macro.
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http://dx.doi.org/10.1007/s11265-021-01714-7 | DOI Listing |
Nurs Open
September 2025
Department of Research, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan.
Aim: The coronavirus disease 2019 (COVID-19) outbreak led to a massive influx of patients into hospitals, thus prompting the implementation of various response mechanisms to manage the surge in number of patients. During the mitigation period, hospital response mechanisms ceased and ensued a return to normal settings. However, changing hospital settings can affect nurses' work environments.
View Article and Find Full Text PDFAcute Crit Care
August 2025
National Brain Center, Iran University of Medical Sciences, Tehran, Iran.
Background: Delirium is an acute condition marked by disturbances in cognition, awareness, and attention, commonly observed in hospitalized patients due to factors such as illness severity and medication. It is particularly prevalent in intensive care unit settings, affecting up to 80% of ventilated patients. This study investigates whether coronavirus disease 2019 (COVID-19) delirium aligns with expectations of non-COVID-19 delirium incidence in other hospitalized patients and identifies unique or common factors contributing to delirium in these groups.
View Article and Find Full Text PDFBiotechnol J
September 2025
Department of Anesthesiology and Intensive Care, Jena University Hospital, Friedrich-Schiller-University, Jena, Germany.
Sepsis remains a major clinical challenge, often resulting in long-term physiological and immunological disturbances. This study employed high-throughput single-cell Raman spectroscopy to analyze the biochemical profiles of peripheral blood leukocytes from patients with non-COVID-19 and COVID-19-associated sepsis. Leukocytes were assessed at multiple timepoints, including the acute phase (Days 3 and 7 after sepsis onset) and late recovery phase (6 and 12 months after sepsis onset).
View Article and Find Full Text PDFSci Rep
August 2025
Department of Medical Biochemistry, Faculty of Medicine, Recep Tayyip Erdogan University, Rize, Turkey.
Coronavirus Disease 2019 (COVID-19), caused by SARS-CoV-2, has posed a significant global public health challenge, with long-term sequelae such as post-COVID-19 syndrome continuing to burden health systems. Tobacco use, a major preventable cause of morbidity and mortality, impairs the immune response and exacerbates respiratory diseases, including COVID-19. Passive smoking, an important but often overlooked public health problem, exposes non-smokers to harmful health risks and may contribute to worse outcomes in respiratory disease.
View Article and Find Full Text PDFSci Rep
August 2025
Department of Global Health Research, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
The COVID-19 pandemic disrupted essential health services worldwide. In sub-Saharan Africa, lockdowns initially controlled virus transmission but later negatively affected non-COVID-19 healthcare. In Uganda, government policies evolved from strict movement restrictions to moderate restrictions with consideration for socioeconomic activities.
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