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Article Abstract

A 72-year-old immunocompromised man infected with severe acute respiratory syndrome coronavirus 2 received bamlanivimab monotherapy. Viral evolution was monitored in nasopharyngeal and blood samples by melting curve analysis of single-nucleotide polymorphisms and whole-genome sequencing. Rapid emergence of spike receptor binding domain mutations was found, associated with a compartmentalization of viral populations.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462331PMC
http://dx.doi.org/10.3201/eid2710.211509DOI Listing

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