Saline nasal irrigation and gargling in COVID-19: Part II. Outcomes in Omicron and risk-benefit for self-care.

Background: The World Health Organization recommends at-home management of mild COVID-19. While our preliminary evaluation provided evidence for saline nasal irrigation (SNI) and gargling in COVID-19, an update and risk-benefit assessment for self-care in Omicron infection is warranted, from treatment and preparedness perspectives, as new SARS-CoV-2 variants continuously emerge, while symptoms overlap with those of common colds and other upper respiratory tract infections.

Methods: Systematic literature searches for preclinical and clinical studies involving Omicron infection and saline, bias assessment, and review of outcomes (benefits, risks).

The State of Michigan Burn Mass Casualty Incident Surge Plan: Leveraging Trauma Centers as Burn Surge Facilities.

The Michigan Burn Mass Casualty Incident (BMCI) Surge Plan provides the framework and guidelines for responding to a BMCI within the state of Michigan. It relies on collaborative efforts across the state, utilizing American College of Surgeons Committee on Trauma (ACS-COT) verified Level I and Level II trauma centers as Burn Surge Facilities (BSFs) in the event of a BMCI, ensuring the best use of resources across the state. Preparation for MCIs with standardized frameworks as illustrated in the Michigan BMCI Surge Plan, as well as through trainings and simulated disaster planning, help ensure effective disaster preparation.

Investigating Injuries to the Anterolateral Corner of the Knee: Imaging Insights Into Kaplan Fibers and the Anterolateral Ligament in Anterior Cruciate Ligament Tears.

Background: The intricate relationship between anterolateral ligament (ALL) and Kaplan fibers (KF) injuries in acute traumatic anterior cruciate ligament (ACL) tears presents a diagnostic challenge. Understanding these associations is crucial for enhancing therapeutic strategies and patient outcomes.

Purpose: To elucidate the prevalence of ALL and KF injuries among patients with acute ACL tears and examine their correlations with other imaging findings.

A Bilateral Wolffian Adnexal Tumor with Malignant Behavior: A Rare Case Report with Literature Review.

Wolffian adnexal tumors (FATWOs) originate from the mesonephric duct remnants. FATWOs are extremely rare and 100 incidental FATWOs have been reported in the English literature as of now. Most FATWOs have low potential for malignancy but aggressive behavior including recurrence and metastasis have been described in few cases; There is no standard protocol for optimal treatment of FATWOs.

Neonatal Nonketotic Hyperglycinemia: A Severe Case With Prenatal Indicators and Comprehensive Review of Recognition and Management.

Nonketotic hyperglycinemia (NKH), also known as glycine encephalopathy, is a rare inherited neurometabolic disorder caused by a deficiency in the glycine cleavage enzyme system (GCS), leading to the pathological accumulation of glycine in blood and cerebrospinal fluid (CSF). This case report details a neonate presenting with central apnea, profound hypotonia, and refractory seizures, alongside prenatal findings of polyhydramnios and hiccup-like fetal movements, all strongly suggestive of severe NKH. Diagnostic evaluation confirmed markedly elevated glycine levels in serum and CSF, with a CSF-to-plasma glycine ratio exceeding 0.