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Purpose: To evaluate the relationship between cerebroplacental ratio (CPR) and the need for operative delivery due to intrapartum fetal compromise (IFC) and adverse perinatal outcome (APO) in appropriate-for-gestational-age (AGA) late-term pregnancies undergoing induction of labor. The predictive performance of CPR was also assessed.
Materials And Methods: Retrospective study including singleton AGA pregnancies that underwent elective induction of labor between 41 + 0 and 41 + 6 weeks and were delivered before 42 + 0 weeks. IFC was defined as persistent pathological CTG or pathological CTG and fetal scalp pH < 7.20. Operative delivery included instrumental vaginal delivery (IVD) and cesarean section (CS). APO was defined as a composite of umbilical artery pH < 7.20, Apgar score < 7 at 5 minutes, and admission to the neonatal intensive care unit for > 24 hours.
Results: The study included 314 women with 32 (10 %) IVDs and 49 (16 %) CSs due to IFC and 85 (27 %) APO cases. Fetuses with CPR < 10 percentile showed a significantly higher rate of operative delivery for IFC (40 % (21/52) vs. 23 % (60/262); p = 0.008) yet not a significantly higher rate of APO (31 % (16/52) vs. 26 % (69/262); p = 0.511). The predictive values of CPR for operative delivery due to IFC and APO showed sensitivities of 26 % and 19 %, specificities of 87 % and 84 %, positive LRs of 2.0 and 1.2, and negative LRs of 0.85 and 0.96, respectively.
Conclusion: Low CPR in AGA late-term pregnancies undergoing elective induction of labor was associated with a higher risk of operative delivery for IFC without increasing the APO rate. However, the predictive value of CPR was poor.
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http://dx.doi.org/10.1055/a-1399-8915 | DOI Listing |
BMJ Glob Health
September 2025
Department of Womens and Child Health, University of Liverpool, Liverpool, UK.
Introduction: Caesarean use in India continues to rise and significant disparities exist. However, women and clinicians' views are under-researched. This paper aims to explore women and clinicians' views and preferences for mode of birth in two government hospitals in urban central India.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
August 2025
State Key Laboratory for Safe Mining of Deep Coal Resources and Environment Protection, Anhui University of Science and Technology, Huainan 232001, China; School of Spatial Informatics and Geomatics Engineering, Anhui University of Science and Technology, Huainan 232001, China. Electronic address: c
Conventional methods for soil sampling and soil water content (SWC) measurement are often labor-intensive and time-consuming. The Pedo-transfer function (PTF) integrating soil spectroscopy with soil physicochemical properties provides a more efficient approach for SWC estimation. However, existing studies highlight regional limitations in the accuracy of PTFs across diverse geographical regions.
View Article and Find Full Text PDFInt J Womens Health
August 2025
School of Nursing and Rehabilitation, Nantong University, Nantong, Jiangsu, People's Republic of China.
Background: Previous studies did not investigate the effect of gradually increasing the concentration of low-dose oxytocin on mother and newborn outcomes. The purpose of this study was to look at the relationship between oxytocin responsiveness and outcomes for both mothers and newborns during labor induction.
Methods: This retrospective cohort study was conducted at Nantong Maternal and Child Health Hospital, and participants were divided into the early reaction to oxytocin group and the later reaction to oxytocin group based on oxytocin response.
J Diabetes Sci Technol
September 2025
Division of Endocrinology, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.
Inpatient hyperglycemia remains a challenge, as conventional insulin regimens often lead to both hyperglycemia and hypoglycemia. Traditional glucose monitoring methods, such as point-of-care testing, fail to detect diurnal and nocturnal glycemic fluctuations, contributing to suboptimal control. This review examines the effectiveness of continuous glucose monitoring (CGM) and automated insulin delivery (AID) systems in managing diabetes in hospitalized patients, including those with additional challenges such as end-stage kidney disease (ESKD), pregnancy, and steroid use.
View Article and Find Full Text PDFGigascience
January 2025
Helmholtz AI, Helmholtz Zentrum Muenchen, 85764 Neuherberg, Germany.
Background: The ability to differentiate between viable and dead microorganisms in metagenomic data is crucial for various microbial inferences, ranging from assessing ecosystem functions of environmental microbiomes to inferring the virulence of potential pathogens from metagenomic analysis. Established viability-resolved genomic approaches are labor-intensive as well as biased and lacking in sensitivity.
Results: We here introduce a new fully computational framework that leverages nanopore sequencing technology to assess microbial viability directly from freely available nanopore signal data.