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Intraocular pressure (IOP) is an essential indicator of the diagnosis and treatment of glaucoma. IOP has an apparent physiological rhythm, and it often reaches its peak value at night. To avoid missing the peak value at night and sample the entire rhythm cycle, the continuous monitoring of IOP is urgently needed. A wearable contact lens IOP sensor based on a platinum (Pt) strain gauge is fabricated by the micro-electro-mechanical (MEMS) process. The structure and parameters of the strain gauge are optimized to improve the sensitivity and temperature stability. Tests on an eyeball model indicate that the IOP sensor has a high sensitivity of 289.5 μV/mmHg and excellent dynamic cycling performance at different speeds of IOP variation. The temperature drift coefficient of the sensor is 33.4 μV/°C. The non-invasive IOP sensor proposed in this report exhibits high sensitivity and satisfactory stability, promising a potential in continuous IOP monitoring.
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http://dx.doi.org/10.3390/mi12020108 | DOI Listing |
Vet Ophthalmol
August 2025
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, USA.
Objective: To determine the accuracy of the EYEMATE-SC suprachoroidal tracer for telemetric tonometry in canine and equine globes.
Procedures: The EYEMATE-SC sensor (7.8 mm × 3.
ACS Sens
August 2025
Center for X-Mechanics, State Key Laboratory of Fluid Power & Mechatronic System, Key Laboratory of Soft Machines and Smart Devices of Zhejiang Province, School of Aeronautics and Astronautics, Zhejiang University, Hangzhou, Zhejiang province 310027, China.
Continuous monitoring of intraocular pressure (IOP) is critical for the diagnosis and management of glaucoma. Flexible piezoresistive wearable devices, featuring high sensitivity and simple signal processing, enable such continuous monitoring. Recently, conductive metal-organic frameworks (MOFs) have shown promising potential in electronic devices due to their coordination self-assembly, which allows integration with various complex substrates for wearable sensor applications.
View Article and Find Full Text PDFACS Omega
August 2025
School of Chemical Engineering, Yeungnam University, 280 Daehak-Ro, Gyeongsan, Gyeongbuk 38541, Republic of Korea.
Microelectromechanical system (MEMS)-based sensors have become essential in various fields, including healthcare, automotive, and industrial applications. These sensors integrate mechanical structures and electronics on a single chip, allowing precise, compact, and efficient measurements of parameters like pressure, force, acceleration, and chemical reactions. In this context, this review article presents the essential role of MEMS sensors in healthcare applications.
View Article and Find Full Text PDFSensors (Basel)
July 2025
School of Information Science and Engineering, Shenyang University of Technology, Shenyang 110870, China.
This study proposes a deep learning-based, non-contact method for detecting elevated intraocular pressure (IOP) by integrating Scheimpflug images with corneal biomechanical features. Glaucoma, the leading cause of irreversible blindness worldwide, requires accurate IOP monitoring for early diagnosis and effective treatment. Traditional IOP measurements are often influenced by corneal biomechanical variability, leading to inaccurate readings.
View Article and Find Full Text PDFOphthalmol Glaucoma
July 2025
Eye Clinic Sulzbach, Knappschaft Hospitals Saar, 66280 Sulzbach/Saar, Germany; Klaus Heimann Eye Research Institute (KHERI), 66280 Sulzbach/Saar, Germany. Electronic address:
Objective: To investigate short- and long-term intraocular pressure (IOP) fluctuations in patients with primary open-angle glaucoma (POAG) after successful nonpenetrating glaucoma surgery (NPGS).
Design: Prospective, open-label, multicenter interventional study.
Subjects: A total of 20 patients with POAG who underwent NPGS combined with permanent implantation of a suprachoroidal telemetric IOP sensor (EyeMate-SC, Implandata Ophthalmic Products GmbH, Hanover, Germany).