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Article Abstract
This study aimed to unveil the functional roles of in hepatocellular carcinoma (HCC). A discovery cohort and a validation cohort were respectively used to identify and verify the clinical value of in HCC. Bioinformatics analysis was performed to explore its potential mechanisms. was upregulated in HCC tissues and serum samples. Survival analysis and receiver operating characteristic curve further revealed its prognostic and diagnostic roles. Exploration of the mechanism showed that might exert a pro-cancer role via the lncRNA-miRNA-mRNA network. Our study reveals that upregulated can serve as a potential diagnostic and prognostic biomarker and provides novel clues as to the role of in HCC.
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| http://dx.doi.org/10.2217/epi-2020-0363 | DOI Listing |
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