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Objective: To evaluate the cost, workflow, and safety of implementing a vial transfer device system.
Methods: In this retrospective analysis, pharmacy systems and electronic health record reports identified high-volume and high-cost medications prepared by a Vial2Bag (V2B) system from July 2017 to June 2018. The major outcome was the extrapolated yearly cost avoidance (EYCA) from utilization of a V2B system, calculated by subtracting total costs of the V2B system from total cost of ready-to-use products and locally compounded sterile products. Secondary outcomes included a workflow and safety analysis.
Results: Implementing a V2B system led to a total EYCA of $2 295 261. A total of 283 209 potential V2B units were available for dispensing from automated dispensing systems and 41 082 yearly sterile product room units were avoided. A 0.02% safety report incidence per V2B administration was calculated at our institution.
Conclusion: Use of a V2B system resulted in a substantial cost avoidance compared to purchasing commercial products and preparing locally compounded sterile products. The V2B system appears to be a safe addition to further optimize workflow but may require further investigation in prospective analyses.
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http://dx.doi.org/10.1177/0897190020938195 | DOI Listing |
NPJ Digit Med
March 2025
Beijing Tongren Eye Center, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology & Visual Sciences Key Lab, Medical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information Technology, Beijing Tongren Hospital,
Early detection, regular monitoring of eyelid tumors and post-surgery recurrence monitoring are crucial for patients. However, frequent hospital visits are burdensome for patients with poor medical conditions. This study validates a novel deep learning-based mobile application, based on YOLOv5 and Efficient-Net v2-B architectures, for self-diagnosing eyelid tumors, enabling improved health support systems for such patients.
View Article and Find Full Text PDFFEBS J
February 2024
Institute for Biological and Chemical Systems - Biological Information Processing (IBCS-BIP), Karlsruhe Institute of Technology (KIT), Eggenstein-Leopoldshafen, Germany.
The vertebrate nervous system is composed of a wide range of neurons and complex synaptic connections, raising the intriguing question of how neuronal diversity is generated. The spinal cord provides an excellent model for exploring the mechanisms governing neuronal diversity due to its simple neural network and the conserved molecular processes involved in neuron formation and specification during evolution. This review specifically examines two distinct progenitor domains present in the zebrafish ventral spinal cord: the lateral floor plate (LFP) and the p2 progenitor domain.
View Article and Find Full Text PDFbioRxiv
March 2023
Molecular Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
Elife
December 2022
Department of Neuroscience, Washington University in St. Louis, St. Louis, United States.
Shared lineage has diverse effects on patterns of neuronal connectivity. In mammalian cortex, excitatory sister neurons assemble into shared microcircuits. In , in contrast, sister neurons with different levels of Notch expression (Notch/Notch) develop distinct identities and diverge into separate circuits.
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