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Early detection, regular monitoring of eyelid tumors and post-surgery recurrence monitoring are crucial for patients. However, frequent hospital visits are burdensome for patients with poor medical conditions. This study validates a novel deep learning-based mobile application, based on YOLOv5 and Efficient-Net v2-B architectures, for self-diagnosing eyelid tumors, enabling improved health support systems for such patients. 1195 preprocessed clinical ocular photographs and biopsy results were collected for model training. The best-performing model was chosen and converted into a smartphone-based application, then further evaluated based on external validation dataset, achieved 0.921 accuracy for triple classification outcomes (benign/malignant eyelid tumors or normal eye), generally superior to that of general physicians, resident doctors, and ophthalmology specialists. Intelligent Eyelid Tumor Screening application exhibited a straightforward detection process, user-friendly interface and treatment recommendation scheme, provides preliminary evidence for recognizing eyelid tumors and could be used by healthcare professionals, patients and caregivers for detection and monitoring purposes.
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http://dx.doi.org/10.1038/s41746-025-01539-9 | DOI Listing |
Ophthalmic Plast Reconstr Surg
September 2025
Division of Surgery, Department of Ophthalmology.
An 84-year-old Caucasian male was referred for evaluation of a worsening left medial canthal lesion for consideration of excision. The patient reported a 4-year history of the painless canthal lesion gradually increasing in size with progressively obstructed peripheral vision. On examination, the cream-colored cyst measured 10 × 8 mm.
View Article and Find Full Text PDFAnn Plast Surg
September 2025
Division of Onco-pathology, Department of Pathology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India.
Background: Ulceroproliferative lesions involving the eyelids can be due to several causes, chief among them being squamous cell carcinoma (SCC). It is imperative to distinguish it from various mimics owing to the limited surgical therapy that can be offered at the site. Inverted follicular keratosis (IFK) is a rare benign epidermal tumor that arises from the infundibular portion of the hair follicle.
View Article and Find Full Text PDFCancer Manag Res
August 2025
Hepatology and Gastroenterology Department, The Third Central Hospital of Tianjin, Tianjin, People's Republic of China.
We describe the case of an older male patient with hepatocellular carcinoma and a history of hepatitis B virus-related cirrhosis and type 2 diabetes mellitus. At 12 weeks after treatment with transcatheter arterial chemoembolization (TACE) combined with systemic therapy using lenvatinib and camrelizumab, the patient was found to have progressive disease, based on the modified Response Evaluation Criteria in Solid Tumors (mRECIST) criteria. He also exhibited symptoms such as left eyelid ptosis and limitations in inward, upward, and downward movements of the left eye.
View Article and Find Full Text PDFJ Dermatol
September 2025
Department of Dermato-Oncology, NHO Kagoshima Medical Center, Kagoshima, Japan.
The treatment of skin malignancies of the lower eyelid presents unique challenges due to the thin skin, proximity to vital structures, and the functional importance of the eyelid. Although surgical excision remains the standard approach for such malignancies, lower eyelid reconstruction is critical for preserving both function and aesthetics. Free tarsoconjunctival grafts (FTGs) have emerged as effective options for posterior lamellar reconstruction, providing structural support and long-term stability.
View Article and Find Full Text PDFEur J Ophthalmol
August 2025
Georgetown University School of Medicine, Washington, District of Columbia, USA.
PurposeSinonasal mucosal melanoma (SNMM) accounts for approximately 4-8% of sinonasal malignancies. SNMM frequently originates in the nasal cavity, causing nonspecific nasal symptoms that inevitably delay diagnosis. Left untreated, the tumor may extend into the orbit.
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