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The monitoring of the contamination levels of bisphenol A (BPA) and its congeners bisphenol B (BPB) and bisphenol F (BPF) in foodstuffs is a necessary process for assessment of consumers' risk. After development and validation of a method using Strata® C18-E cartridge cleanup with detection by liquid chromatography coupled to tandem mass spectrometry, forty-six samples of fruit juices, sold on Italian markets, have been analysed to assess the concentration of BPA, BPB and BPF. BPB and BPF were not detected in any samples, BPA was found in 33 % of the samples. The observed levels ranged from 0.50 ng mL to 2.85 ng mL. Potential Daily Intakes (PDI) of BPA for Italian populations were calculated by the budget method model. PDIs ranged from 0.012 to 0.285 μg kg bw day. None of the calculated values exceeded the current temporary TDI of 4 μg kg bw day.
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http://dx.doi.org/10.1080/19440049.2019.1657967 | DOI Listing |
Environ Int
August 2025
National Engineering Research Center of Industrial Wastewater Detoxication and Resource Recovery, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address:
Perinatal exposure to bisphenol A (BPA) promotes the development of inflammatory and immune diseases. Nevertheless, the potential mechanisms of this effect and the developmental immunotoxicity of BPA analogs are unclear. Here, embryonic zebrafish were exposed to a range of concentrations of BPA and its analogs.
View Article and Find Full Text PDFJ Chromatogr A
July 2025
Key Laboratory of Public Health Safety, MOE, School of Public Health, Fudan University, Shanghai 200032, China; College of Medicine, Xizang University, Lhasa 850000, China; Key Laboratory of Pubic Health Safety & Policy Research, Xizang University, Lhasa City, 850000, China. Electronic address: ying
The global replacement of Bisphenol A (BPA) with structurally similar yet understudied analogues demands precise biomonitoring tools to assess human exposure and health risks. To bridge critical gaps, we developed a novel ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for simultaneous quantification of 15 emerging BPA analogues including Bisphenol AF (BPAF), Bisphenol AP (BPAP), Bisphenol B (BPB), Bisphenol C (BPC), Bisphenol E (BPE), Bisphenol F (BPF), Bisphenol G (BPG), Bisphenol FL (BPFL), Bisphenol M (BPM), Bisphenol P (BPP), Bisphenol pH (BPPH), Bisphenol S (BPS), Bisphenol TMC (BPTMC), Bisphenol Z (BPZ), and Bisphenol A diglycidyl ether (BFDGE)-in human serum and urine matrices. The method achieved ultrahigh sensitivity with limits of detection (LODs) of 0.
View Article and Find Full Text PDFInt J Hyg Environ Health
July 2025
Departments of Environmental Health, Epidemiology and Biostatistics, Harvard T.H. Chan School of Public Health, 677 Huntington Ave., Boston, MA, 02115, USA.
Background: Phenols are a family of short-lived endocrine disrupting chemicals found in a wide range of products and have drawn significant attention because of widespread human exposure and their potential adverse effects on reproductive health. Phenols have been widely detected in several human bodily fluids, particularly in urine and blood. However, there is limited data on phenols in human ovarian follicular fluid (FF).
View Article and Find Full Text PDFJ Hazard Mater
September 2025
State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 100049, China; School of Environment, Hangzh
Given the intricate regulation of endocrine homeostasis, the crosstalk among multiple nuclear receptors (NRs) induced by emerging chemicals has garnered increasing attention. Of particular, the interaction between estrogen receptor alpha (ERα) and retinoic acid receptor alpha (RARα) is now a new focus of research. Herein, six representative analogs of bisphenol A (i.
View Article and Find Full Text PDFJ Hazard Mater
September 2025
The Sperm Laboratory, College of Life Sciences, Zhejiang University, Hangzhou 310058, China. Electronic address:
Bisphenol A (BPA) is a well-known environmental pollutant, particularly in aquatic systems. The hazards of BPA exist in the following aspects, such as endocrine interference, reproductive system impact, development problems and metabolic disorders, and so on. As an economically important aquatic crustacean, Eriocheir sinensis lives in a wide range of BPA contaminated water environments.
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