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Article Abstract
Complex oil of and seed (ZPCO) is used as a traditional medicine due to its pharmacological activities. The aim of this study was to investigate the immunostimulatory effect of ZPCO in isolated splenocytes as well as in an immunosuppressed rat model, which was generated via oral administration of cyclophosphamide. Notably, our results showed that ZPCO exerted an immunity-enhancing effect both and . Specifically, ZPCO treatment enhanced the viability and inflammatory cytokine production of splenocytes and NK cell activity Moreover, this product improved host defense under immunosuppressive conditions by increasing the number of immune cells and promoting the expression of cytokines involved in immune responses. Our results suggest that complex oil including should be explored as a novel immunostimulatory agent that could potentially be used for therapeutic purposes or as an ingredient in functional foods.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196913 | PMC |
| http://dx.doi.org/10.1155/2018/8107326 | DOI Listing |
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