The past, present and future of protein-based materials.

Open Biol

Department of Interdisciplinary Science, Centre for Synthetic and Systems Biology, Institute for Quantitative Biology, Biochemistry and Biotechnology, School of Biological Sciences, University of Edinburgh, Edinburgh, UK

Published: October 2018


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Protein-based materials are finding new uses and applications after millennia of impacting the daily life of humans. Some of the earliest uses of protein-based materials are still evident in silk and wool textiles and leather goods. Today, even as silks, wools and leathers are still be used in traditional ways, these proteins are now seen as promising materials for biomaterials, vehicles of drug delivery and components of high-tech fabrics. With the advent of biosynthetic methods and streamlined means of protein purification, protein-based materials-recombinant and otherwise-are being used in a host of applications at the cutting edge of medicine, electronics, materials science and even fashion. This commentary aims to discuss a handful of these applications while taking a critical look at where protein-based materials may be used in the future.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223211PMC
http://dx.doi.org/10.1098/rsob.180113DOI Listing

Publication Analysis

Top Keywords

protein-based materials
16
materials
6
future protein-based
4
protein-based
4
materials protein-based
4
materials finding
4
finding applications
4
applications millennia
4
millennia impacting
4
impacting daily
4

Similar Publications

Cancer remains a critical global health concern, affecting individuals across all age groups and claiming millions of lives annually. Early detection is essential, as it significantly improves prognosis and enhances survival rates. However, conventional diagnostic techniques, despite their accuracy, are often expensive, time-consuming, and inaccessible in remote or resource-limited areas.

View Article and Find Full Text PDF

Smart textile interfaces based on protein structure-reconstructed bovine serum albumin hydrogel fibers for disability support.

J Colloid Interface Sci

August 2025

Hubei Provincial Key Laboratory of Green Materials for Light Industry, Hubei University of Technology, Wuhan 430068, China. Electronic address:

Human-machine interaction (HMI) textile interfaces with safe ingredients for intelligent wearable sensing systems are critical in the era of information and the metaverse. To address the dual limitations of traditional synthetic polymer hydrogels (poor biocompatibility) and pure protein-based materials (limited mechanical performance), this study has redesigned the protein structure for a bovine serum albumin (BSA)-based composite hydrogel fibers system. By leveraging the synergistic interplay of dynamic ionic crosslinking and covalent crosslinking, the hydrogel system achieves enhancements in both mechanical strength and processability.

View Article and Find Full Text PDF

Hydrogel biomaterials offer great promise for three-dimensional cell culture and therapeutic delivery. Despite many successes, challenges persist in that gels formed from natural proteins are only marginally tunable whereas those derived from synthetic polymers lack intrinsic bioinstructivity. Toward the creation of biomaterials with both excellent biocompatibility and customizability, recombinant protein-based hydrogels have emerged as molecularly defined and user-programmable platforms that mimic the proteinaceous nature of the extracellular matrix.

View Article and Find Full Text PDF

From Lignocellulosic Residues to Protein Sources: Insights into Biomass Pre-Treatments and Conversion.

Polymers (Basel)

August 2025

MED-Mediterranean Institute for Agriculture, Environment and Development, CHANGE-Global Change and Sustainability Institute, Faculdade de Ciências e Tecnologia, Universidade do Algarve, Campus de Gambelas, Ed. 8, 8005-139 Faro, Portugal.

With the global population steadily rising, the demand for sustainable protein sources has become increasingly urgent. Traditional animal- and plant-based proteins face challenges related to scalability, resource efficiency, and environmental impact. In this context, single-cell protein has emerged as a promising alternative.

View Article and Find Full Text PDF

Meat analog manufacturing via high-moisture extrusion technology is a complex process wherein the properties of protein materials constitute a critical determining factor. In this study, we enhanced the fiber structure properties of high-moisture extruded peanut protein-based meat analogs by incorporating different starches (cassava starch, acetyl distarch phosphate [ADSP], and hydroxypropyl starch) to address challenges in water retention, emulsification, and digestibility. The impact of the starch content (0, 3, 6, 9, 12%) was assessed using low-field nuclear magnetic resonance, ultraviolet/fluorescence spectroscopy, differential scanning calorimetry, sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and functional tests.

View Article and Find Full Text PDF