98%
921
2 minutes
20
Oligonucleotide probes were designed with a poly-cytosine region that facilitates stable anchoring to a magnetic ionic liquid support. By tethering a recognition sequence to the poly-C tag, the resulting diblock oligonucleotides distinguished single-nucleotide variants and captured DNA targets from interfering genomic DNA and cell lysate for qPCR amplification.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1039/c8cc05954c | DOI Listing |
Inorg Chem
September 2025
Institute of Inorganic and Analytical Chemistry, University of Münster, Corrensstraße 28/30, 48149 Münster, Germany.
Isovalent anion substitution has been shown to have a tremendous effect on the transport properties in lithium halide solid ionic conductors. Although sodium-ion solid state batteries based on chloride ionic conductors have recently gathered significant attention, investigations of anion substitution in sodium containing chlorides remain scarce. Here, we investigate the role of Br isoelectronic anion substitution in a perovskite-related compound with nominal composition of NaTaCl.
View Article and Find Full Text PDFAdv Mater
September 2025
Department of Engineering, School of Computing and Engineering, University of Huddersfield, Queensgate, Huddersfield, HD1 3DH, UK.
A new family of nanostructured ternary intermetallic compounds - named the ZIP phases - is introduced in this work. The ZIP phases exhibit dualistic atomic ordering, i.e.
View Article and Find Full Text PDFSmall
September 2025
School of Materials Science and Engineering, State Key Laboratory of Silicon and Advanced Semiconductor Materials, Zhejiang University, Hangzhou, 310027, P. R. China.
High-concentration electrolytes (HCEs) face inherent challenges such as high viscosity and diminished ionic conductivity caused by the formation of three-dimensional (3D) anion networks, which limit their practical applications. In this study, it is demonstrated that encapsulating HCEs within metal-organic frameworks (MOFs) effectively disrupts these 3-D networks, resulting in significantly enhanced ionic conductivity. Raman spectroscopy, nuclear magnetic resonance (NMR), and molecular dynamics (MD) simulations reveal a significant reduction in aggregates (AGGs)-state anion within MOF-confined electrolytes, confirming the reconstruction of the solvation environment.
View Article and Find Full Text PDFMikrochim Acta
September 2025
Department of Public Health Laboratory Sciences, College of Public Health, Hengyang Medical School, University of South China, 28 Changsheng West Road, Hengyang, 421001, Hunan, China.
We systematically evaluated the DNA adsorption and desorption efficiencies of several nanoparticles. Among them, titanium dioxide (TiO₂) nanoparticles (NPs), aluminum oxide (Al₂O₃) NPs, and zinc oxide (ZnO) NPs exhibited strong DNA-binding capacities under mild conditions. However, phosphate-mediated DNA displacement efficiencies varied considerably, with only TiO₂ NPs showing consistently superior performance.
View Article and Find Full Text PDFJ Chem Phys
September 2025
Fakultät Physik, Technische Universität Dortmund, D-44221 Dortmund, Germany.
The dynamics of the different constituents of the ionic liquid 1-hexyl-3-methylimidazolium chloride (HmimCl) is investigated using nuclear magnetic resonance including chlorine relaxometry, line shape analysis, and proton-detected diffusometry, as well as frequency-dependent shear mechanical measurements. This combination of techniques is useful to probe the individual motions of the anions and the cations, and the sample's overall flow response. The 35Cl- dynamics appears to be close to the structural (or α-) relaxation as seen by rheology.
View Article and Find Full Text PDF