Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Objective: The aim of this study was to compare the bactericidal effect of various laser irradiation systems on Enterococcus faecalis biofilms in dentinal tubules by using a novel dentin infection model and confocal laser scanning microscopy (CLSM).
Background Data: Laser-activated irrigations have been proposed as an adjuvant to conventional protocols of root canal treatment to enhance the smear layer removal, which is a promising protocol for root canal disinfection.
Materials And Methods: E. faecalis were centrifuged into the dentinal tubules, cultured for 3 weeks, and then received 1- and 3-min treatments as follows: (A) 5.25% sodium hypochlorite (NaOCl) irrigation, (B) Nd:YAG laser irradiation, (C) diode laser irradiation, (D) Nd:YAP laser irradiation, (E) Er,Cr:YSGG laser-activated NaOCl irrigation, and (F) Er:YAG laser-activated NaOCl irrigation. Bacterial reductions were assessed by CLSM using a LIVE/DEAD bacterial viability stain method.
Results: For each group, the bacterial reduction increased as the treatment time increased (p < 0.05). The Er,Cr:YSGG and Er:YAG laser significantly enhanced the bactericidal effect of NaOCl (p < 0.05). Under the conditions of the same treatment time, bacterial reductions were presented in the descending order of Er:YAG + NaOCl, Er,Cr:YSGG + NaOCl > Nd:YAP > Nd:YAG, diode > NaOCl.
Conclusions: Under the conditions of present study, treatments of Er:YAG + NaOCl and Er,Cr:YSGG + NaOCl presented the strongest bactericidal effect among the tested protocols and are potential protocols for root canal disinfection.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1089/pho.2017.4430 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Clinical comparison of four commercial MRI phantoms on a 0.35T MR-linac using a standard clinical TRUFI sequence at a single institution.
J Appl Clin Med Phys
September 2025
Department of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia, USA.
Purpose: Real‑time magnetic resonance-guided radiation therapy (MRgRT) integrates MRI with a linear accelerator (Linac) for gating and adaptive radiotherapy, which requires robust image‑quality assurance over a large field of view (FOV). Specialized phantoms capable of accommodating this extensive FOV are therefore essential. This study compares the performance of four commercial MRI phantoms on a 0.
View Article and Find Full Text PDF5-Aminolevulinic acid-mediated photodynamic therapy improves scar healing of laryngeal wounds in rats.
Lasers Med Sci
September 2025
Department of Otolaryngology Head and Neck Surgery, BenQ Medical Center, The Affiliated BenQ Hospital of Nanjing Medical University, 71 Hexi Street, Nanjing 210019, Jiangsu, China.
To evaluated the efficacy of photodynamic therapy (PDT) in improving laryngeal mucosal wound scar healing in vivo and investigated its underlying mechanisms. Laryngeal mucosal wounds were induced in Sprague-Dawley rats. Two weeks post-injury, PDT was administered via intraperitoneal injection of 100 mg/kg 5-aminolevulinic acid (5-ALA) and 635-nm red laser irradiation at varying energy doses (15, 30, and 45 J/cm²).
View Article and Find Full Text PDFFrom fundamentals to applications: magnetic nanoparticles for MRI imaging and NIR-induced thermal activation in tissue-mimicking environments.
J Mater Chem B
September 2025
Biomolecular Physics Department, Faculty of Physics, Babes-Bolyai University, 1 M. Kogalniceanu Street, 400084, Cluj-Napoca, Romania.
Magnetic nanoparticles are widely explored in biomedical applications, particularly as MRI contrast agents and for magnetic hyperthermia. However, their photothermal capabilities under near-infrared (NIR) irradiation remain underexplored in realistic, tissue-like environments. This study provides a comprehensive assessment of ultrasmall FeO nanoparticles (9.
View Article and Find Full Text PDFA Diselenide-Based Triple-Responsive Nanogel for Tumor Chemo-Photoimmunotherapy.
ACS Appl Mater Interfaces
September 2025
State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, People's Republic of China.
In this study, we successfully developed a diselenide-based, triple-responsive intelligent nanogel, IR780@BEAP, for lung cancer therapy. Exploiting the elevated levels of reactive oxygen species (ROS) and glutathione (GSH) in the tumor microenvironment (TME), a ROS/GSH dual-responsive diselenide cross-linker (DSe5) was synthesized and used to cross-link betulin (BE) with polysaccharide (AP) while coloading the photosensitizer IR780. The resulting nanogel, IR780@BEAP, exhibited an appropriate particle size (137.
View Article and Find Full Text PDFEffects of intravenous laser irradiation on viral load and T lymphocytes in people living with HIV/AIDS.
Rev Esc Enferm USP
September 2025
Universidade Estadual Paulista, Faculdade de Medicina, Botucatu, SP, Brazil.
Objective: To evaluate the effectiveness of intravenous laser irradiation of blood in reducing viral load and increasing LT-CD4+ and LT-CD8+ in people living with HIV/AIDS.
Method: Randomized, controlled, parallel, single-blind clinical trial. Twenty-eight participants were allocated to the intervention (ILIB n = 15) and control (CTRL n = 13) groups.