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Biofilms are deleterious in many biomedical and industrial applications and prevention of their formation has been a pressing challenge. Here, carbon dots, CDs-LP that were easily synthesized from the biomass of one-step hydrothermal carbonization, were demonstrated to prevent biofilm formation of . CDs-LP did not thwart the growth of , indicating the anti-biofilm effect was not due to the bactericidal effect. Moreover, CDs-LP did not affect the growth of the animal cell AT II, showing low cytotoxicity, good safety and excellent biocompatibility. Therefore, CDs-LP could overcome the cytotoxicity issue found in many current antibiofilm agents. CDs-LP represent a new type of anti-biofilm materials, opening up a novel avenue to the development of biofilm treatment.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820432 | PMC |
http://dx.doi.org/10.3389/fmicb.2018.00259 | DOI Listing |
Macromol Biosci
September 2025
Department of Chemistry and Biochemistry, Concordia University, Montreal, Quebec, Canada.
Timely and accurate assessment of wounds during the healing process is crucial for proper diagnosis and treatment. Conventional wound dressings lack both real-time monitoring capabilities and active therapeutic functionalities, limiting their effectiveness in dynamic wound environments. Herein, we report our proof-of-concept approach exploring the unique emission properties and antimicrobial activities of carbon nanodots (CNDs) for simultaneous detection and treatment of bacteria.
View Article and Find Full Text PDFLangmuir
September 2025
Centre for Biomedical Engineering, Indian Institute of Technology, Delhi, New Delhi 110016, India.
The study addresses the critical issue of sepsis diagnosis, a life-threatening condition triggered by the body's immune response to infection that leads to mortality. Current diagnostic methods rely on the time-consuming assessment of multiple biomarkers by a series of tests, leading to delayed treatment. Here, we report a platform for developing a point-of-care (POC) device utilizing electrochemical immunosensors for the dual and rapid detection of sepsis biomarkers: Procalcitonin (PCT), Interleukin-6 (IL-6), and C-reactive protein (CRP) as host markers and lipopolysaccharide (LPS) as a pathogen marker.
View Article and Find Full Text PDFACS Nano
September 2025
State Key Laboratory of Materials-Oriented Chemical Engineering, National Engineering Research Center for Special Separation Membrane, Nanjing Tech University, Nanjing 210009, China.
Airborne pathogens and pollution control typically necessitate multiple membranes, each specializing in efficient aerosol filtration, moisture regulation, or antimicrobial protection. Integrating all these functions into a single membrane is highly advantageous but remains inherently challenging due to material incompatibility and inevitable performance trade-offs. Here, we present a photoactive Janus nanofibrous membrane for highly efficient air purification, engineered via sequential electrospinning.
View Article and Find Full Text PDFNanoscale Adv
August 2025
Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research S.A.S. Nagar Mohali 160062 Punjab India
Nitrosamines are genotoxic, mutagenic impurities and are widely encountered in the global landscape of the pharmaceutical industry. There is a need for rapid detection of nitrosamines in a pharmaceutical product. Here, we report the synthesis of carbon quantum dots (CQDs) using a readily available carbon precursor.
View Article and Find Full Text PDFRSC Adv
September 2025
Laboratory of Constitution and Reaction of Matter, UFR SSMT, Felix Houphouet Boigny University Abidjan 22 BP 582 Cote d'Ivoire.
Melamine is an additive used fraudulently to enrich foods with nitrogen, particularly in the dairy industry. It is also known as the main metabolite or degradation phytosanitary product of cyromazine. However, the numerous incidents involving living beings in aquatic environments, children and pets fed with products made from melamine in China and certain African countries have led to distrust of melamine in food.
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