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The Asian tiger mosquito, appears to have been extirpated from Palmyra Atoll following rat eradication. Anecdotal biting reports, collection records, and regular captures in black-light traps showed the species was present before rat eradication. Since then, there have been no biting reports and no captures over 2 years of extensive trapping (black-light and scent traps). By contrast, the southern house mosquito, was abundant before and after rat eradication. We hypothesize that mammals were a substantial and preferred blood meal for , whereas feeds mostly on seabirds. Therefore, after rat eradication, humans and seabirds alone could not support positive population growth or maintenance of This seems to be the first documented accidental secondary extinction of a mosquito. Furthermore, it suggests that preferred host abundance can limit mosquito populations, opening new directions for controlling important disease vectors that depend on introduced species like rats.
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http://dx.doi.org/10.1098/rsbl.2017.0743 | DOI Listing |
Anal Chem
September 2025
Marshall Laboratory of Biomedical Engineering, Shenzhen Key Laboratory for Nano-Biosensing Technology, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen, Guangdong 518060, China.
Chronic periodontitis, a frequent complication of diabetes, is exacerbated by bacterial biofilms that drive progressive periodontal tissue destruction and systemic inflammation. Conventional treatments, utilizing mechanical debridement and systemic antibiotics, often fail to eradicate bacterial biofilms, promote antibiotic resistance, and lack real-time monitoring, leading to suboptimal therapeutic outcomes. Herein, we report a separable bilayer microneedle (MN) patch that enables localized, antibiotic-free, biofilm-targeted therapy and in situ biomarker-based monitoring for the integrated management of chronic periodontitis.
View Article and Find Full Text PDFSci Rep
September 2025
Department of Materials Engineering, Isfahan University of Technology, Isfahan, 84156-83111, Iran.
Treating infected wounds is a major clinical challenge, and concerns about bacterial resistance have driven the shift toward natural antimicrobials over antibiotics. Herein, a 3D printed scaffold wound dressing consisting of alginate (Alg) and fucoidan (F) was prepared, and Soluplus (Sol) nanomicelles (NMs) were used to load vanillin (Vn) as a lipophilic antibacterial agent into the 3D printed scaffold. Characterization analyses revealed that the fabricated scaffold exhibited a peak swelling capacity of 294.
View Article and Find Full Text PDFJ Colloid Interface Sci
August 2025
Marine College, Shandong University, Weihai 264209, China. Electronic address:
The clinical treatment of infected skin injuries caused by exogenous bacteria presents significant challenges, and traditional therapies struggle to achieve multiple therapeutic effects simultaneously. Herein, a mussel-inspired photothermal antibacterial self-repairing hydrogel (BA-PDZn-N) was designed for accelerating infected wound healing. Multi-network structures were constructed through free radical polymerization and dynamic borate bonding between acrylamide, 3-acrylamidophenylboronic acid, and polydopamine (PDA), as well as metal ligand chelation between PDA and Zn for uniform porosity.
View Article and Find Full Text PDFAdv Sci (Weinh)
August 2025
College of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Periodontitis is a multifactorial inflammatory disease involving pathogenic biofilm formation, amplified oxidative stress, and impaired tissue regeneration. In addition to its complicated pathology, effective treatment of periodontitis is challenged by a dynamic oral microenvironment that prevents drug retention. To overcome these issues, an anti-bacterial, ROS-scavenging, and tissue-regenerative hydrogel system (HQUP@TF127) is developed.
View Article and Find Full Text PDFBiomaterials
August 2025
Research Center for Nano Biomaterials, Analytical & Testing Center, Sichuan University, Chengdu, 610064, PR China. Electronic address:
The treatment of infectious bone defects requires simultaneous resolution of bacteria-associated antibiotic resistance, inflammatory microenvironment dysregulation, and impaired bone regeneration. Here, we developed an injectable, self-assembling designed gelatin micro-/nano-sphere system (GHMs@G1-N-A/T) that addresses the tripartite challenges of infectious bone defects through innovative material engineering: Antibacterial module featuring aptamer-conjugated gelatin nanospheres (AGN-Apt/Te) for MRSA-specific targeting, coupled with dual enzyme/pH-responsive release mechanisms (gelatinase-triggered nanosphere detachment and MgO-derived ROS generation); A self-assembling microsphere scaffold (GHMs) constructed through vanillin-mediated crosslinking and nano-hydroxyapatite (n-HA)/MgO incorporation, enabling sequential release of Mg/Ca; and A gelatinase-sensitive peptide (G-1) interface that dynamically links these components, ensuring microenvironment-responsive functionality. Results demonstrated that gelatinase-triggered AGN-Apt/Te nanospheres detachment enabled bacteria-specific antibiotic delivery, achieving greater than 95 % eradication of S.
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