Mussel-inspired photothermal antibacterial multi-network hydrogel for cascade-enhanced infected wound healing.

The clinical treatment of infected skin injuries caused by exogenous bacteria presents significant challenges, and traditional therapies struggle to achieve multiple therapeutic effects simultaneously. Herein, a mussel-inspired photothermal antibacterial self-repairing hydrogel (BA-PDZn-N) was designed for accelerating infected wound healing. Multi-network structures were constructed through free radical polymerization and dynamic borate bonding between acrylamide, 3-acrylamidophenylboronic acid, and polydopamine (PDA), as well as metal ligand chelation between PDA and Zn for uniform porosity.