Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Apoferritin caged gold nanoparticles (AuNPs) were assembled into flower-like structures by precise base pairing of the attached DNA molecules. The key step was to use the eight hydrophilic channels through the apoferritin to control the exact number and locations of the DNA molecules that grafted onto the caged AuNP.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c6cc09858d | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Mechanistic roles of long non-coding RNAs in DNA damage response and genome stability.
Mutat Res Rev Mutat Res
September 2025
Institute of Environmental Medicine, Zhejiang University School of Medicine, Hangzhou 310058, China. Electronic address:
To maintain genomic stability, cells have evolved complex mechanisms collectively known as the DNA damage response (DDR), which includes DNA repair, cell cycle checkpoints, apoptosis, and gene expression regulation. Recent studies have revealed that long non-coding RNAs (lncRNAs) are pivotal regulators of the DDR. Beyond their established roles in recruiting repair proteins and modulating gene expression, emerging evidence highlights two particularly intriguing functions.
View Article and Find Full Text PDFIdentification of Targetable Mutations in Ovarian Cancer.
JCO Precis Oncol
September 2025
Division of Hematology and Oncology, University of California Los Angeles, Los Angeles, CA.
Purpose: mutations are classically seen in non-small cell lung cancers (NSCLCs), and EGFR-directed inhibitors have changed the therapeutic landscape in patients with -mutated NSCLC. The real-world prevalence of -mutated ovarian cancers has not been previously described. We aim to determine the prevalence of pathogenic or likely pathogenic mutations in ovarian cancer and describe a case of -mutated metastatic ovarian cancer with a durable response to osimertinib, an EGFR-directed targeted therapy.
View Article and Find Full Text PDFDNA Binding and Electrochemical Characterization of Oxidative Products of the Cobalt(II) Complex.
J Phys Chem B
September 2025
National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei 11221, Taiwan, ROC.
The synthesis of -tetrakis(3,4,5-trimethoxyphenyl)porphyrin [HT(3,4,5-OCH)PP] and cobalt(II) -tetrakis(3,4,5-trimethoxyphenyl)porphyrin [Co(T(3,4,5-OCH)PP)] has been successfully accomplished. The oxidation properties of [Co(T(3,4,5-OCH)PP)] have been assessed through UV-vis, NMR, and EPR techniques. It can be seen in the UV-vis spectrum that adding SbCl caused extra peaks to appear at 674 nm, which means that a π-cation radical was formed.
View Article and Find Full Text PDFClonal Hematopoiesis in Nonmalignant Disease: Functional Consequences of Mutated Immune Cells by Clonal Hematopoiesis in the Diseased Tissue.
Annu Rev Pathol
September 2025
3Department of Pathology, Stanford University, Stanford, California, USA;
Clonal hematopoiesis, originally identified as a precursor to hematologic malignancies, has emerged as a significant factor in various nonmalignant diseases. Recent research highlights how somatic mutations in hematopoietic stem cells lead to the expansion of circulating mutated immune cells that exert profound effects on organ function and disease progression. These mutated clones display altered inflammatory profiles and tissue-specific functional consequences, contributing to various diseases including atherosclerotic cardiovascular disease, osteoporosis, heart failure, and neurodegenerative conditions.
View Article and Find Full Text PDFEvidence for extensive diversity in the pollen-parasitic genus in western North America, including two new species associated with lichens.
Mycologia
September 2025
Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada.
Understanding the diversity of microscopic hyphomycetes is an ongoing effort, and many species remain undescribed. While studying lichen organismal composition in western Canada, metagenomic data revealed the presence of an unknown species of (, Ascomycota), a genus of pollen-parasitic fungus with no previous records in the region. We developed genus-specific primers to amplify DNA in lichen and adjacent substrate extractions, successfully detecting multiple lineages of across a wide geographic range within North America.
View Article and Find Full Text PDF