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Background: Breastfeeding is believed to reduce children's risk for obesity but data are conflicting. It is also uncertain if breastfeeding has different effects on obesity in high- and low-income countries.
Objectives: This study aimed to investigate the association between having been breastfed and body mass index (BMI) in 6- to 7-year-old children in a large international survey.
Methods: Parents/guardians reported whether their child had been breastfed and their current height and weight. Some centres measured height and weight directly. Analyses adjusted for whether height and weight were reported or measured, child's age, sex, country gross national income and centre.
Results: Data were available for 76,635 participants from 31 centres in 18 countries. Reported breastfeeding rates varied from 27 to 98%. After adjusting for potential confounders, the estimated BMI difference was 0.04 kg m(-2) lower among those who had been breastfed (P = 0.07). The risk for being overweight or obese was slightly lower among breastfed children (odds ratio = 0.95, P = 0.012). There was no evidence that the association between breastfeeding and BMI was different in lower income countries compared with higher income countries.
Conclusions: The findings suggest that breastfeeding has little impact on children's BMI. Increasing breastfeeding is unlikely to reduce the global epidemic of childhood obesity.
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http://dx.doi.org/10.1111/ijpo.266 | DOI Listing |
JAMA Netw Open
September 2025
Perelman School of Medicine, University of Pennsylvania, Philadelphia.
Importance: As obesity rates rise in the US, managing associated metabolic comorbidities presents a growing burden to the health care system. While bariatric surgery has shown promise in mitigating established metabolic conditions, no large studies have quantified the risk of developing major obesity-related comorbidities after bariatric surgery.
Objective: To identify common metabolic phenotypes for patients eligible for bariatric surgery and to estimate crude and adjusted incidence rates of additional metabolic comorbidities associated with bariatric surgery compared with weight management program (WMP) alone.
Aquac Nutr
August 2025
College of Fisheries, Hunan Agricultural University, Changsha 410128, China.
An 8-week feeding trial was conducted to assess the effects of hydrolyzed feather meal (HFM) as a fish meal replacement on the growth performance, flesh quality, skin color, and intestinal microbiota of yellow catfish (). Five isonitrogen (44% crude protein) and isolipidic (8.5% crude lipid) diets were formulated with varying levels of HFM at 0% (FM, control), 2.
View Article and Find Full Text PDFMedicine (Baltimore)
September 2025
Department of Biostatistics and Epidemiology, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Subclinical hypothyroidism (SCH) is biochemically characterized by elevated thyrotropin (thyroid-stimulating hormone [TSH]) levels, while free thyroxine (FT4) levels remain normal. Given the high prevalence of vitamin D deficiency in Iran, investigating the association between vitamin D levels and SCH may improve treatment. A case-control study was conducted at the endocrinology clinic of Imam Khomeini Hospital, affiliated with Ahvaz Jundishapur University of Medical Sciences.
View Article and Find Full Text PDFMedicine (Baltimore)
September 2025
Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
The association between asthma and chronic obstructive pulmonary disease overlap (ACO) and insulin resistance (IR) has not been adequately investigated. Triglyceride glucose (TyG) index-related obesity indices offer a novel measure for assessing IR. We aimed to explore the associations between these indices and ACO in US population.
View Article and Find Full Text PDFMedicine (Baltimore)
September 2025
The Third Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.
Background: Multiple non-pharmacological and nonsurgical interventions have demonstrated efficacy in improving abdominal obesity. However, the optimal intervention remains uncertain. This study aimed to assess the relative effectiveness and safety of these interventions in reducing waist circumference, waist-to-hip ratio, waist-to-height ratio (WHtR), body mass index (BMI), and body weight among adults with abdominal obesity.
View Article and Find Full Text PDF