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First International Workshop on Streptococcus suis, Beijing, China, 12-13 August 2013. This second and final chapter of the report on the First International Workshop on Streptococcus suis follows on from Part 1, published in the April 2014, volume 9, issue 4 of Future Microbiology. S. suis is a swine pathogen and a zoonotic agent afflicting people in close contact with infected pigs or pork meat. Although sporadic cases of human infections had been reported worldwide, deadly S. suis outbreaks emerged in Asia. The severity of the disease underscores the lack of knowledge on the virulence and zoonotic evolution of this human-infecting agent. The pathogenesis of the infection, interactions with host cells and new avenues for treatments were among the topics discussed during the First International Workshop on S. suis (China 2013).
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http://dx.doi.org/10.2217/fmb.14.15 | DOI Listing |
Transbound Emerg Dis
September 2025
International Joint Research Center of National Animal Immunology, Ministry of Education Key Laboratory for Animal Pathogens and Biosafety, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
is an important zoonotic pathogen that can cause severe infections in both humans and pigs. The prevalence of serotype 14 in sporadic cases in China has been gradually increasing during recent years. However, the current understanding of serotype 14 is limited.
View Article and Find Full Text PDFVet Res
September 2025
State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Streptococcus suis, an important zoonotic pathogen capable of transmission from pigs to humans, represents a critical threat to both public health and the global pork industry. The increasing prevalence of multidrug-resistant S. suis strains, coupled with their ability to form biofilms, has necessitated the development of alternative antimicrobial strategies.
View Article and Find Full Text PDFInt J Antimicrob Agents
August 2025
MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210014, China;; Key Lab of Animal Bacteriology, Ministry of Agriculture and Rural Affairs, Nanjing 210014, China;; WOAH Reference Lab for Swine Strep
Streptococcus suis is an important zoonotic pathogen that causes severe diseases in both humans and pigs, with β-lactam antibiotics serving as the primary treatment. However, resistance to penicillin and amoxicillin has been steadily increasing, and the mechanisms underlying their resistance remain poorly understood. In this study, we analyzed 534 S.
View Article and Find Full Text PDFBMC Genomics
August 2025
Institute of Bacterial Infections and Zoonoses, Federal Research Institute for Animal Health, Friedrich-Loeffler-Institute, Naumburger Str. 96a, 07743, Jena, Germany.
Background: Bacterial genome exploration and outbreak analysis rely heavily on robust whole-genome sequencing and bioinformatics analysis. Widely-used genomic methods, such as genotyping and detection of genetic markers demand high sequencing accuracy and precise genome assembly for reliable results.
Methods: To assess the utility of nanopore sequencing for genotyping highly pathogenic bacteria with low mutation rates, we sequenced six reference strains using Oxford Nanopore Technologies (ONT) R10.
Commun Biol
August 2025
State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, China.
Meningitis caused by Streptococcus suis serotype 2 (SS2) in humans and pigs is an acute nervous disorder associated with serious sequelae. Bacterial meningitis is tightly associated with immune cell responses and the local immune microenvironment. However, the dynamic changes of the immune system during the disease progression in the brain remains unclear.
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