Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Encapsulated Fe3O4 nanoparticles of average diameters d = 12 nm are obtained by coprecipitation, in the presence of 2-methoxyethanol hemiester of poly(maleic anhydride-alt-butyl vinyl ether) 5% grafted with poly(ethylene glycol) (VP-MAG nanoparticles). A complete characterization of nude and encapsulated nanoparticles through structural techniques (namely XRD, TEM, SEM), Raman spectroscopy and magnetic measurements has been performed. These nanoparticles compared with commercial compounds (ENDOREM®) present superparamagnetic behavior and nuclear relaxivities that make them promising as magnetic resonance imaging (MRI) contrast agents (CAs). We found that our nanostructures exhibit r2 relaxivity higher than those of commercial CAs over the whole frequency range. The MRI efficiency of our samples was related to their microstructural and magnetic properties.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c3dt32805h | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Next-Generation Nanoparticle-Enabled mRNA Vaccines in the Treatment of COVID-19.
Crit Rev Ther Drug Carrier Syst
January 2025
The emergence of messenger ribonucleic acid (mRNA) vaccines as an alternative platform to traditional vaccines has been accompanied by advances in nanobiotechnology, which have improved the stability and delivery of these vaccines through novel nanoparticles (NPs). Specifically, the development of NPs for mRNA delivery has facilitated the loading, protection and release of mRNA in the biological microenvironment, leading to the stimulation of mRNA translation for effective intervention strategies. Intriguingly, two mRNA vaccines, BNT162b2 (Pfizer-BioNTech) and mRNA-1273 (Moderna), have been permitted for emergency usage authorization to prevent COVID-19 infection by USFDA.
View Article and Find Full Text PDFNanomedicine-Mediated Therapies to Target Cancer Stem Cells: An Emerging Technology.
Crit Rev Ther Drug Carrier Syst
January 2025
Department of Biotechnology, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi 110062, India.
Cancer stem cells (CSCs) are a category of cancer cells endowed with the ability to renew themselves, undergo unregulated growth, and exhibit a differentiation capacity akin to that of normal stem cells. CSCs have been linked with tumor metastasis and cancer recurrence due to their ability to elude immune monitoring. As a result, targeting CSCs specifically may improve the efficacy of cancer therapy.
View Article and Find Full Text PDFPeptide Sequence Modulating the Analytical Performance of Electrogenerated Chemiluminescence Peptide-Based Biosensors for Matrix Metalloproteinase 2.
Anal Chem
September 2025
Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710062, P. R. China.
Electrogenerated chemiluminescence (ECL) methods have been widely used in clinical diagnosis. Although ECL peptide-based biosensors continue to grow with good sensitivity and signal flexibility, little emphasis has been placed on the effect of the peptide sequence on ECL sensitivity. We herein studied the nuanced effects of different peptide sequences on the analytical performance of ECL peptide-based biosensors for matrix metalloproteinase 2 (MMP-2) assay, in which [(pbz)Ir(DMSO)Cl] (pbz = 3-(2-pyridyl)benzoic acid) was used as the ECL emitter while a specific peptide was used as the molecular recognition element.
View Article and Find Full Text PDFLeveraging dietary fiber's natural physiology: from dietary insights to nanoscale IBD intervention.
Crit Rev Food Sci Nutr
September 2025
Food Safety Key Laboratory of Zhejiang Province, School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou, China.
The prevalence of inflammatory bowel disease (IBD), including crohn's disease and ulcerative colitis, is rising worldwide. Among various potential contributors, low dietary fiber (DF) diet habit stands out as a substantial factor in this accelerating trend. Conversely, DF supplementation inhibits the manifestation of IBD pathology and promotes inflammatory remission.
View Article and Find Full Text PDFCobalt-Doped Carbon Quantum Dots Work Synergistically with Weak Acetic Acid to Eliminate Antimicrobial-Resistant Bacterial Infections.
ACS Nano
September 2025
Department of Biomedicine, University of Bergen, Bergen 5009, Norway.
When pathogenic bacteria colonize a wound, they can create an alkaline ecological niche that selects for their survival by creating an inflammatory environment restricting healthy wound healing to proceed. To aid healing, wound acidification has been exploited to disrupt this process and stimulate fibroblast growth, increase wound oxygen concentrations, minimize proteolytic activity, and restimulate the host immune system. Within this study, we have developed cobalt-doped carbon quantum dot nanoparticles that work together with mild acetic acid, creating a potent synergistic antimicrobial therapy.
View Article and Find Full Text PDF