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The diffuse-reflectance FTIR spectroscopy (DRIFTS) and attenuated total reflection FTIR (ATR-FTIR) were used to study polygonum multi florum Thumb and its extracts. The result shows that when acetone is used as extraction agent, the contents of extracts in polygonum multi florum Thunb's phloem are highest, those in polygonum multi florum Thunb's xylem are the lowest. Compared with DRIFTS and ATR-FTIR, it can be found that there are some differences between polygonum multi florum Thunb and its extracts. There are two gentle absorption peaks at 3 576 and 3 147 cm(-1) respectively for polygonum multi florum Thunb, while there is a strong absorption peak at 3 351 cm(-1) for its extracts, showing that there may be more OH... active ingredients in polygonum multi florum Thunb's extracts. Meanwhile, polygonum multiflorum Thunb has strong absorption peaks at 931, 859, 766 and 709 cm(-1) respectively, while its extracts have no resembling absorption peaks. It also shows that the extracts are active ingredients.
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Int J Mol Sci
April 2025
College of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang 550025, China.
The global rise in aging populations has made healthy longevity a critical priority in medical research. 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside (TSG), the primary bioactive component of Thunb. (commonly known as Thunb.
View Article and Find Full Text PDFJ Ethnopharmacol
April 2025
Jiangsu Key Laboratory of Neuropsychiatric Disease and College of Pharmaceutical Science, Suzhou Medical College, Suzhou International Joint Laboratory for Diagnosis and Treatment of Brain Diseases, Soochow University, 215127, Suzhou, Jiangsu Province, China. Electronic address:
Ethnopharmacological Relevance: Clinical applications of Polygonum multiflorum Thunb. (PMT) have occasionally reported adverse effects on liver function, linking these instances of hepatotoxicity to PMT samples. Evaluating the hepatotoxicity of PMT, given its intricate composition and mechanisms, presents a notable challenge.
View Article and Find Full Text PDFFront Pharmacol
November 2024
State Key Laboratory of Component-based Chinese Medicine, Tianjin Key Laboratory of TCM Chemistry and Analysis, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
shows dual hepatoprotective and hepatotoxic effects. The bioactive components responsible for these effects are unknown. This study investigates whether -2,3,5,4'-tetrahydroxystilbene-2-O--D-glucoside (-TSG), a stilbene glycoside, has hepatoprotective and/or hepatotoxic effects in a liver injury model.
View Article and Find Full Text PDFInt J Biol Macromol
November 2024
College of Forestry, Beijing Forestry University, Beijing 100083, PR China.
Sporopollenin is a natural biological macromolecule consisting of highly cross-linked carbon, hydrogen, and oxygen atoms, with a highly porous structure and multifunctional groups. In this work, a novel surface molecularly imprinted polymer based on magnetically aminated cattail sporopollenin (MACSp-SMIP) was prepared for the specific and efficient adsorption of resveratrol, with the aim of purifying resveratrol from Polygonum cuspidatum extracts. MACSp-SMIP was found to have a porous structure covered with the multi-layered sponge-like imprinted polymers.
View Article and Find Full Text PDFPhytomedicine
November 2024
Key Laboratory of TCM-information Engineer of State Administration of TCM, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China. Electronic address:
Background: Polygoni Cuspidati Rhizoma et Radix (Huzhang in Chinese), refers to the root and rhizome of Polygonum cuspidatum Sieb. et Zucc. Huzhang is commonly used in clinical practice for the prevention and treatment of diabetes and its complications, but its active components and regulatory mechanisms have not yet been thoroughly analyzed.
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