Profile of asymmetrical retinopathy of prematurity in twins.

Indian J Ophthalmol

Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110 029, India.

Published: July 2010


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Article Abstract

Background: In twin births, both babies have the same gestational age and pre-natal conditions. However, twins may develop a varied retinopathy of prematurity (ROP) course depending on birth weight and other systemic factors.

Objective: To study the profile of asymmetric ROP in twins

Design: Retrospective study.

Setting: Tertiary ROP referral eye hospital.

Materials And Methods: The profile of 56 pairs of twins with ROP were studied and analyzed for differences in zone or need for treatment, while studying possible causes for the varied outcome.

Results: In 45 pairs of twins (80%) the disease progressed identically in both eyes, while in 11 pairs (20%) the ROP showed differences in zone or need for treatment. Four of these pairs were discordant. In 3 of these 4 pairs, the heavier birth weight twin had a more severe ROP course.

Conclusions: Twins can present with asymmetric ROP course, and it is therefore essential to examine both twins as per screening protocols.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886251PMC
http://dx.doi.org/10.4103/0301-4738.62645DOI Listing

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