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Five new and 15 known anthraquinones have been isolated from Plocama pendula root cultures transformed by Agrobacterium rhizogenes. The new anthraquinones were named balonone, balonone methyl ether, and plocamanones A, B, and C. Moreover, lucidin dimethyl ether was obtained for the first time as a natural compound. On the other hand, a study of P. pendula natural roots afforded another two new anthraquinones, i.e., plocamanone D and chionone. The anthraquinone isozyganein dimethyl ether has been isolated for the first time from nature. Another 19 known anthraquinones were also obtained from the natural roots.
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http://dx.doi.org/10.1002/cbdv.200800047 | DOI Listing |
Biology (Basel)
August 2025
School of Life Science and Engineering, Lanzhou University of Technology, Lanzhou 730050, China.
Rhubarb, a medicinal herb in Gansu Province, China, undergoes significant quality changes during sun-drying. This study investigated color changes, drying kinetics, anthraquinone (AQ) content, metabolic profiles, and enzyme activity during the process. Results showed that drying induced enzymatic browning, with the browning index (BI) progressively increasing over extended drying periods (4-16 h) and with greater slice thickness (2-8 mm).
View Article and Find Full Text PDFPhytother Res
September 2025
State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
MicroRNAs (miRNAs) have emerged as critical regulators in the pathogenesis of diabetes mellitus (DM) and its associated complications via orchestrating key cellular processes. Natural bioactive components such as flavonoids, polysaccharides, saponins, alkaloids, terpenoids, as well as anthraquinones derived from berries, herbs, vegetables, and fishes have been extensively demonstrated to treat or prevent DM and related complications through targeting miRNAs-mediated signaling pathways. Mechanistically, these compounds treat/prevent DM and its complications principally by modulating processes including glucose homeostasis, inflammatory response, oxidative stress, apoptosis, and autophagy, neovascularization, and fibrosis.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
September 2025
Frontiers Science Center for High Energy Material, Key Laboratory of Cluster Science, Ministry of Education, Beijing Key Laboratory of Photoelectronic/Electrophotonic Conversion Materials, School of Interdisciplinary Science, School of Chemistry and Chemical Engineering, Beijing Institute of Technol
Hydrogen peroxide (HO) is a green oxidant widely used in a variety of industries. Photocatalytic generation of HO from water and oxygen by sunlight is an appealing strategy compared to the high energy consumption of the industrial anthraquinone process. However, the low activity and selectivity of the two-step single-electron oxygen reduction reaction (ORR) during the photocatalytic process greatly restricts the HO production efficiency.
View Article and Find Full Text PDFAdv Sci (Weinh)
August 2025
Jiangsu Co-Innovation Centre of Efficient Processing and Utilization of Forest Resources, College of Chemical Engineering, Nanjing Forestry University, Nanjing, 210037, China.
Organic electrode materials (OEMs) derived from natural quinones can enable sustainable lithium-ion batteries (LIBs) if their dissolution-induced capacity fading in organic electrolytes and their conductivity issues are addressed. It is demonstrated that converting natural anthraquinones (AQs) into organic alkali-metalated salts effectively inhibits their dissolution in aprotic electrolytes. For this purpose, a solubility indicator (ΔMPI) is developed, which reliably guides the selection of compatible OEMs and electrolytes.
View Article and Find Full Text PDFViruses
August 2025
Andevir, University Bordeaux, CNRS, Microbiologie Fondamentale et Pathogénicité, UMR 5234, F-33000 Bordeaux, France.
Integrase is a key protein during HIV-1 replication as it catalyzes the integration of viral DNA into the host DNA. After several decades of research, highly potent and selective active site inhibitors have emerged. The new challenge is now to develop molecules with an original mode of action, targeting integrase out of its catalytic site.
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