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Objectives: The purpose of our study was to assess the potential for radiation dose reduction in digital postinterventional digital mammograms after marker placement.
Materials And Methods: One hundred consecutive cases of marker placement (hook-wire localization or postbiopsy clip marker placement), with 200 full-field digital baseline mammograms (craniocaudal and mediolateral), were included in this prospective trial. For the postinterventional digital mammograms, the milliampere seconds were reduced either by 50% or by 75%. Dose-reduced images were evaluated for sufficient image quality to verify the position of the marker.
Results: In 193 of 200 cases (96.5%), image quality was sufficient to verify the correct position of the marker. One (1%) case with insufficient image quality occurred in the 50% dose-reduction group and 6 (6%) in the 75% dose-reduction group (P = 0.06).
Conclusion: Our results indicate that under evaluation of each individual case, a dose reduction of 50% to 75% can be recommended in postinterventional digital mammograms.
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http://dx.doi.org/10.1097/01.rli.0000163743.63063.9f | DOI Listing |
Nutr Metab Cardiovasc Dis
August 2025
Center for Cohort Studies, Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Background And Aims: Although secondhand smoke (SHS) exposure has been linked with metabolic syndrome (MetS) in never-smokers, its effects among individuals who have quit smoking remain unclear. This study investigated the relationship between changes in SHS exposure and incident MetS in a large cohort of Korean former smokers.
Methods And Results: We analyzed 17,269 Korean former smokers without MetS at baseline from a longitudinal cohort, with a median follow-up of three years.
Proc Biol Sci
September 2025
Department of Biology, Emory University, Atlanta, GA, USA.
Crowding can result in greater disease transmission, yet crowded hosts may also remove infectious propagules from the environment, thereby lowering the encounter rate and infectious dose received by conspecifics. We combined experimental and modelling work to examine the impact of crowding of butterfly larvae on the per-capita risk of infection by a protozoan that is transmitted via the larval food plant, and the resulting infection load in adult butterflies. We reared larvae at different densities and exposed them to low and high doses of parasites.
View Article and Find Full Text PDFClin Gastroenterol Hepatol
September 2025
Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium. Electronic address:
Background And Aims: Infliximab and ustekinumab clearance have been suggested as predictors of disease activity in patients with inflammatory bowel diseases. We aimed to investigate the benefits of clearance monitoring for predicting endoscopic outcomes in patients with Crohn's disease (CD).
Methods: Data from patients with moderate-to-severe CD starting infliximab (n=108) and ustekinumab (n=80) therapy were repurposed.
Clin J Am Soc Nephrol
September 2025
Kidney Division, Peking University First Hospital, Peking University Institute of Nephrology; Key Laboratory of Kidney Disease, Ministry of Health of China; Key Laboratory of Chronic Kidney Disease Prevention and Treatment (Peking University), Ministry of Education, China.
Background: The Therapeutic Effects of Steroids in IgA Nephropathy Global (TESTING) trial demonstrated that glucocorticoid therapy reduced proteinuria and improved kidney outcomes in patients with Immunoglobulin A Nephropathy (IgAN). Galactose-deficient IgA1 (Gd-IgA1) plays a central role in IgAN pathogenesis by promoting immune complex formation. However, the effects of glucocorticoid on pathogenic IgA levels remain unclear.
View Article and Find Full Text PDFLasers Med Sci
September 2025
Department of Otolaryngology Head and Neck Surgery, BenQ Medical Center, The Affiliated BenQ Hospital of Nanjing Medical University, 71 Hexi Street, Nanjing 210019, Jiangsu, China.
To evaluated the efficacy of photodynamic therapy (PDT) in improving laryngeal mucosal wound scar healing in vivo and investigated its underlying mechanisms. Laryngeal mucosal wounds were induced in Sprague-Dawley rats. Two weeks post-injury, PDT was administered via intraperitoneal injection of 100 mg/kg 5-aminolevulinic acid (5-ALA) and 635-nm red laser irradiation at varying energy doses (15, 30, and 45 J/cm²).
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