Predictive Analysis of Dental Caries Risk via Rapid Urease Activity Evaluation in Saliva Using a ZIF-8 Nanoporous Membrane.

Despite a decrease in the incidence of dental caries over the past four decades, it remains a widespread public health concern. The multifactorial etiology of dental caries complicates effective prevention and early intervention efforts, underscoring the need for the development of rapid predictive methods that account for multiple factors. In this study, we selected the activity of urease secreted by as a metabolic marker for dental caries.

Repeatable and renewable synthesis of nickel-iron nitrate hydroxide needle-like arrays for water electrolysis.

A sustainable approach utilizing a low-temperature molten salt strategy is employed in this study to fabricate homogeneous and dense NiFe nitrate hydroxide needle-like arrays on a NiFe foam substrate. The electrode also achieves an ultra-low voltage of 1.77 V at 100 mA cm and maintains stability for more than 120 h at a current density of 100 mA cm, showing excellent overall water splitting (OWS) performance and stability.

Postoperative jaundice related to and gene mutations: A case report and literature review.

Background: Patients with obstructive jaundice caused by intrahepatic bile duct stones can be effectively managed by surgery. However, some patients may develop postoperative complications, liver failure, and other life-threatening situations. Here, we report a patient with mutations in the uridine 5'-diphospho-glucuronosyltransferase 1A1 () and bile salt export pump (adenosine triphosphate-binding cassette subfamily B member 11, ) genes who presented multiple intrahepatic bile duct stones and cholestasis, and the jaundice of the patient increased after partial hepatectomy.

Construction and Evaluation of Zeolitic Imidazolate Framework-Encapsulated Hemoglobin Microparticles as Oxygen Carriers.

Artificial oxygen carriers, such as favorably hemoglobin-based oxygen carriers, have received considerable attention due to some drawbacks of human donor blood. Among all oxygen carriers, the metal organic framework (MOF) exhibits excellent oxygen-carrying capacity due to its good encapsulation efficiency and competitive biocompatibility. Recently, zeolitic imidazolate frameworks (ZIFs) with unique structure have attracted much attention due to their outstanding solvothermal stability.

PNP Nanofluidic Transistor with Actively Tunable Current Response and Ionic Signal Amplification.

Inspired by electronic transistors, electric field gating has been adopted to manipulate ionic currents of smart nanofluidic devices. Here, we report a PNP nanofluidic bipolar junction transistor (nBJT) consisting of one polyaniline (PANI) layer sandwiched between two polyethylene terephthalate (PET) nanoporous membranes. The PNP nBJT exhibits three different responses of currents (quasi-linear, rectification, and sigmoid) due to the counterbalance between surface charge distribution and base voltage applied in the nanofluidic channels; thus, they can be switched by base voltage.

Surface-Enhanced Raman Scattering Probing the Translocation of DNA and Amino Acid through Plasmonic Nanopores.

DNA and amino acids are important biomolecules in living organisms. Probing such biomolecules with structural characters can provide valuable information for life study. Here, gold plasmonic nanopores (GPNs) with high SERS activity (a local enhancement factor higher than 10) are synthesized at the tip of a glass nanopipette.

An in situ SERS study of ionic transport and the Joule heating effect in plasmonic nanopores.

Understanding the ionic transport behaviour as well as temperature change caused by the Joule heating effect is important for the application of plasmonic nanopores. To explore the basic properties of ionic transport through nanopores, we assemble gold nanoparticles on the tip of a glass nanopipette to form a hydrophilic gold porous structure (hydro-GPS) that exhibits high Raman activity.

Paper-based analytical devices for electrochemical study of the breathing process of red blood cells.

Herein we utilized the filter paper to physically trap red blood cells (RBC) to observe the breathing process of red blood cells based on the permeability of the filter paper. By integrating double-sided conductive carbon tape as the working electrodes, the device could be applied to monitor electrochemical responses of RBC for up to hundreds of minutes. The differential pulse voltammetry (DPV) peak currents increased under oxygen while decreased under nitrogen, indicating that RBC could take in and release oxygen.

Paper-based electroanalytical devices for in situ determination of salicylic acid in living tomato leaves.

Detection of phytohormones in situ has gained significant attention due to their critical roles in regulating developmental processes and signaling for defenses in plants at low concentration. As one type of plant hormones, salicylic acid has recently been found to be one of pivotal signal molecules for physiological behaviors of plants. Here we report the application of paper-based electroanalytical devices for sensitively in situ detection of salicylic acid in tomato leaves with the sample volume of several microliters.

Quantum dot (QD)-modified carbon tape electrodes for reproducible electrochemiluminescence (ECL) emission on a paper-based platform.

Stable and sensitive electrochemiluminescence (ECL) detection relies on successful immobilization of quantum dots (QDs) on working electrodes. Herein, we report a new technique to apply double-sided carbon adhesive tape as the working electrode to improve the stability and reproducibility of QD-based ECL emission. CdS QD-modified electrodes were prepared by dropping and drying CdS QD suspension on the carbon adhesive tape supported by indium tin oxide (ITO) glass.