Effectiveness of Susceptibility-Guided Therapy for Infection: A Retrospective Analysis by Propensity Score Matching.

Purpose: This study evaluates and compares the eradication rates of Helicobacter pylori (H. pylori) achieved through susceptibility-guided therapy (SGT) based on resistance genotyping and empirical therapy (ET).

Patients And Methods: A retrospective study was conducted at Beijing Chaoyang Hospital (2021-2023) on patients with H.

Nicotine aggravates pancreatic fibrosis in mice with chronic pancreatitis via mitochondrial calcium uniporter.

Introduction: This study aimed to investigate the effects of nicotine on the activation of pancreatic stellate cells (PSCs) and pancreatic fibrosis in chronic pancreatitis (CP), along with its underlying molecular mechanisms.

Methods: This was an and study. , PSCs were cultured to study the effects of nicotine on their activation and oxidative stress.

Mitochondria oxidative stress mediated nicotine-promoted activation of pancreatic stellate cells by regulating mitochondrial dynamics.

Nicotine, one of the main ingredients of cigarettes, promotes activation of pancreatic stellate cells(PSCs) and exacerbates pancreatic fibrosis in previous studies. Here we focus on the inner relationship between mitochondrial oxidative stress and mitochondrial dynamics to explore the possible mechanism. Primary human PSCs were stimulated by nicotine.

Nicotine facilitates pancreatic fibrosis by promoting activation of pancreatic stellate cells via α7nAChR-mediated JAK2/STAT3 signaling pathway in rats.

Aim: Smoking has been considered as a risk factor of chronic pancreatitis (CP), but the potential mechanism is still unknown. The major pathological feature of CP is pancreatic fibrosis, whose major functional cells are pancreatic stellate cells (PSCs). Nicotine is the major component of cigarette smoke, our recent study suggested that nicotine has the potential to facilitate pancreatic fibrosis in CP.

Tetrafunctional Epoxy Resin-Based Buoyancy Materials: Curing Kinetics and Properties.

In order to synthesize a new kind of buoyancy material with high-strength, low-density and low-water-absorption and to study the curing reaction of tetraglycidylamine epoxy resin with an aromatic amine curing agent, the non-isothermal differential scanning calorimeter (DSC) method is used to calculate the curing kinetics parameters of N,N,N',N'-tetraepoxypropyl-4,4'-diaminodiphenylmethane epoxy resin (AG-80) and the m-xylylenediamine (m-XDA) curing process. Further, buoyancy materials with different volume fractions of hollow glass microsphere (HGM) compounded with a AG-80 epoxy resin matrix were prepared and characterized. The curing kinetics calculation results show that, for the curing reaction of the AG-80/m-XDA system, the apparent activation energy increases with the conversion rates increasing and the reaction model is the Jander equation (three-dimensional diffusion, 3D, n = 1/2).

Nicotine promotes activation of human pancreatic stellate cells through inducing autophagy via α7nAChR-mediated JAK2/STAT3 signaling pathway.

Aim: Pancreatic stellate cells (PSCs) are the main functional cells leading to pancreatic fibrosis. Nicotine is widely considered as an independent risk factor of pancreatic fibrosis, but the mechanism is still unclear. Our study was aimed to explore the effects of nicotine on human pancreatic stellate cells (hPSCs) and involved pathways.

Curing and Characteristics of N,N,N',N'-Tetraepoxypropyl-4,4'-Diaminodiphenylmethane Epoxy Resin-Based Buoyancy Material.

Buoyancy material is a type of low-density and high-strength composite material which can provide sufficient buoyancy with deep submersibles. A new buoyancy material with N,N,N',N'-tetraepoxypropyl-4,4'-diaminodiphenylmethane epoxy resin (AG-80) and m-xylylenediamine (m-XDA) curing agent as matrix and hollow glass microsphere (HGM) as the filler is prepared. The temperature and time of the curing process were determined by the calculations of thermal analysis kinetics (TAK) through differential scanning calorimetry (DSC) analysis.

Bivariate optimization of orthodontic mini-implant thread height and pitch.

Purpose: Mini-implants have been used as anchorage for years, but failure is common in clinical practice. Mini-implant design is a critical factor affecting its stability. The aim of this study was to evaluate the effect of continuous and simultaneous variations of thread height and pitch on the biomechanical properties of an orthodontic mini-implant.

[Clinical study of repair the defect of immediate implant by acellular dermal matrix].

Objective: To evaluate the clinical effect of acellular dermal matrix allograft in repairing the oral mucosal defect of immediate implant.

Methods: 51 cases underwent immediate implant surgery for 67 implants right after the teeth or roots extracted. The mucosal defect of implant areas were repaired by acellular dermal matrix.