A Novel Morphological Classification to Guide Transcatheter Mitral Valve Edge-to-Edge Repair for Commissural Mitral Regurgitation.

Background: Mitral commissural prolapse poses significant anatomical challenges that can hinder the effectiveness of transcatheter edge-to-edge repair (TEER).

Objectives: The aim of this study was to estimate the safety and effectiveness of applying a novel morphological classification to guide TEER in patients with commissural degenerative mitral regurgitation (DMR).

Methods: In this prospective, multicenter study across 18 centers in China, we classified patients with severe commissural DMR into 4 morphological types through detailed echocardiographic analysis.

Exploring the psychological impacts of air contamination: A cross-national study.

This research examines the detrimental effects of air pollution on mental well-being across different countries, exploring whether air pollution acts as a causal factor in deteriorating mental health. The findings demonstrate that heightened air pollution levels are correlated with an increase in mental health issues, including anxiety and depression, primarily through factors like healthcare costs, obesity, and employment instability. The impact is notably more severe in developing countries and colder regions.

The economic consequence of large-scale epidemic outbreak: The path and loss evaluation of COVID-19 in China based on input-output analysis.

The COVID-19 pandemic has significantly impacted China's economic and social development. Understanding the direct and indirect effects of the epidemic on the economy is vital for formulating scientifically grounded epidemic management policies. This study assesses the economic losses and influence paths of a large-scale epidemic in China.

Differential expression profiles and functional analysis of long non-coding RNAs in calcific aortic valve disease.

Aim: To evaluate the expression profile of long non-coding RNAs (lncRNAs) in calcific aortic valve disease (CAVD) and explore their potential mechanism of action.

Methods: The gene expression profiles (GSE153555, GSE148219, GSE199718) were downloaded from the Gene Expression Omnibus (GEO) database and FastQC was run for quality control checks. After filtering and classifying candidate lncRNAs by differentially expressed genes (DEGs) and weighted co-expression networks (WGCNA) in GSE153555, we predicted the potential cis- or trans-regulatory target genes of differentially expressed lncRNAs (DELs) by using FEELnc and established the competitive endogenous RNA (ceRNA) network by miRanda, more over functional enrichment was analyzed using the ClusterProfiler package in R Bioconductor.

Feasibility study of temporary permanent pacemaker in patients with conduction block after TAVR.

Background: Limited data exist on the use of temporary permanent pacemaker (TPPM) to reduce unnecessary PPM in patients with high-degree atrioventricular block (HAVB) after transcatheter aortic valve replacement (TAVR).

Objectives: This study aims to determine the feasibility of TPPM in patients with HAVB after TAVR to provide prolonged pacing as a bridge.

Materials And Methods: One hundred and eleven consecutive patients undergoing TAVR were screened from August 2021 to June 2022.

A novel anatomic classification to guide transcatheter aortic valve replacement for pure aortic regurgitation.

Background: The success of transcatheter aortic valve replacement (TAVR) in native aortic regurgitation (AR) is limited by the absence of calcified anchoring structures. We sought to evaluate transfemoral TAVR in patients with native AR using a novel aortic root imaging classification.

Methods: From March to November 2021, 81 patients with severe AR were prospectively enrolled in 2 cardiac centers in China.

Health shock, medical insurance and financial asset allocation: evidence from CHFS in China.

Background: As health care cost is taking an increasingly substantial proportion of national wealth, health shocks and the subsequent medical expenditures have become increasingly vital contributions to financial risks. However, the individual or combined effects of social and financial medical insurance on household financial behaviors are poorly understood. This research aims to examine the effect of health shocks on financial asset mobility and portfolio allocation of the household.

Evaluation of the safety and efficacy of a novel Anatomical classification and dUal anchoRing theory to Optimize the tavR strategy for pure severe Aortic regurgitation (AURORA): a prospective cohort study.

Background: Success rate of transcatheter aortic valve replacement (TAVR) in aortic regurgitation (AR) patients is relatively low on account of the absence of calcified anchoring structures. Morphological classification and corresponding TAVR strategies for AR are lacking yet.

Methods: The AURORA study is a prospective, multicenter, single-arm cohort study to evaluate the safety and efficacy of transfemoral TAVR for severe AR in patients with high or prohibitive risk for surgery.

Evaluating PM -Related health costs in China-Evidence from 140 Chinese cities.

Introduction: In recent years, China's economy has grown rapidly, and the health condition of Chinese residents has significantly improved. However, this rapid economic and social development has also brought a series of environmental problems, such as serious haze pollution, of which the main contents are PM particles. The objective of this study is to quantitatively estimate the PM -related health costs in China.

The aging burden of hospitalization for heart failure in Chinese populations: evidence from the Macao Heart Failure Study.

Objective: To assess the aging burden of hospitalization for heart failure in Chinese populations in Macao.

Methods: The Macao Heart Failure Study consists of patients hospitalized with a diagnosis of acute heart failure (AHF) at Centro Hospitalar Conde de São Januário (the only public hospital that provides medical care for the approximately 600, 000 residents of Macao) from January 2014 to December 2016. First, we investigated the relationship between socioeconomic development and epidemiological characteristics of HF in Macao.

Does environmental pollution inhibit urbanization in China? A new perspective through residents' medical and health costs.

Health problems caused by environmental pollution may affect the process of urbanization in China. Therefore, this study, against the backdrop of promoting new-type urbanization, evaluates the level of China's urbanization comprehensively using the fully arranged polygon graphical index method. It uses a dynamic threshold panel model to study the potential non-linear relationship between environmental pollution (wastewater, sulfur dioxide, and solid wastes) and urbanization under different health costs of residents.

Does sanitation infrastructure in rural areas affect migrant workers' health? Empirical evidence from China.

Health is considered the most important factor for individual well-being and a country's sustainable development. Among the influential factors of population health, sanitary infrastructure, particularly sanitary toilets and innocuous-sanitary toilets, have already attracted attention. In recent years, to improve the overall health status of rural residents, the Chinese government has promoted the "toilet revolution" in rural areas to update and modernize the facilities of toilets.

The impact of environmental pollution on public health expenditure: dynamic panel analysis based on Chinese provincial data.

In recent years, along with rapid economic growth, China's environmental problems have become increasingly prominent. At the same time, the level of China's pollution has been growing rapidly, which has caused huge damages to the residents' health. In this regard, the public health expenditure ballooned as the environmental quality deteriorated in China.

[Normal reference values and predict equations of heart function].

Objective: For heart functional parameters, we commonly used normal range. The reference values and predict formulas of heart functional parameters and their relationships with individual characteristics are still lack.

Methods: Left ventricular (LV) volumes (end-diastolic volume and end-systolic volume), stroke volume (SV), ejection fraction (EF) and cardiac output (CO) were measured by cardiac CT angiography (CAT) in 1 200 healthy Caucasian volunteers, men 807 and women 393, and age 20-90yr.