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The COVID-19 pandemic has significantly impacted China's economic and social development. Understanding the direct and indirect effects of the epidemic on the economy is vital for formulating scientifically grounded epidemic management policies. This study assesses the economic losses and influence paths of a large-scale epidemic in China. We proposed three COVID-19 scenarios - serious, normal, and mild - to evaluate the direct economic impact on China's GDP from a demand perspective. An input-output model was used to estimate the indirect impact. Our findings show that China's GDP could lose 94,206, 75,365, and 56,524 hundred million yuan under serious, normal, and mild scenarios, respectively, with corresponding GDP decline rates of 9.27%, 7.42%, and 5.56%. Under the normal scenario, indirect economic loss and total loss are projected at 75,364 and 489,386 hundred million yuan, respectively. Additionally, the pandemic led to a reduction in carbon emissions: direct emissions decreased by 1,218.69 million tons, indirect emissions by 9,594.32 million tons, and total emissions by 10,813.01 million tons across various industries. This study provides a comprehensive analysis of the economic and environmental impacts of the pandemic.
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http://dx.doi.org/10.1080/17441692.2024.2341403 | DOI Listing |
J Neurol
September 2025
Multiple Sclerosis Center, Sheba Medical Center, Derech Sheba 2, Tel Hashomer, Israel.
Introduction: Psychological stress has been proposed as a trigger for disease activity in multiple sclerosis (MS), but findings have been inconsistent. While prior research has focused largely on chronic stressors, little is known about how people with MS (pwMS) cope with acute, large-scale stress events such as war.
Objective: Examine the effects of wartime stress following the October 7, 2023 attack on disease activity in pwMS, and to assess whether emotional factors are associated with relapse risk during this period.
Allergol Immunopathol (Madr)
September 2025
Department of Respiratory Disease, Children's Hospital Affiliated to Shandong University, Jinan, China.
Background: Asthma is a chronic respiratory disease with complex pathogenesis. Some studies suggest that certain trace metals may be associated with asthma. However, the relationship between serum copper (Cu) and childhood asthma remains unclear.
View Article and Find Full Text PDFInfect Prev Pract
September 2025
Department of Hygiene and Epidemiology, School of Medicine, University of Thessaly, Larisa, Greece.
Background: Vaccinations are considered one of the most effective medical interventions. Among other benefits, certain vaccinations help reduce antimicrobial resistance by decreasing antibiotic use. Considering reports of increased antimicrobial resistance during the COVID-19 pandemic, this study aimed to explore the relationship between COVID-19 vaccination status and antibiotic use in COVID-19 patients.
View Article and Find Full Text PDFJ Bacteriol
September 2025
Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Essential genes are interesting in their own right and as potential antibiotic targets. To date, only one report has identified essential genes on a genome-wide scale in , a problematic pathogen for which treatment options are limited. That foundational study used large-scale transposon mutagenesis to identify 404 protein-encoding genes as likely to be essential for vegetative growth of the epidemic strain R20291.
View Article and Find Full Text PDFFront Pharmacol
August 2025
Department of Education and Support for Regional Medicine (General and Kampo Medicine), Tohoku University Hospital, Sendai, Japan.
Introduction: Traditional Japanese (Kampo) medicine containing kernel (KPK) is prescribed for treating menstrual- and pregnancy-related symptoms. However, no safety information is available regarding its use in pregnant women. In this study, we examined the associations of KPK prescriptions during the first trimester of pregnancy with preterm births and major congenital malformations (MCMs) in newborns.
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