Pilot study of ultrasound-guided microwave ablation for inactivating excess remnant thyroid after surgery in patients with differentiated thyroid cancer.

Objectives: To evaluate the safety and efficacy of ultrasound (US)-guided microwave ablation (MWA) for inactivating excess remnant thyroid (RT) after surgery in patients with differentiated thyroid cancer (DTC).

Methods: This study was registered in the Chinese Clinical Trial Registry under the identifier ChiCTR2200063200 on September 1, 2022. This study enrolled consecutive postsurgery DTC patients who were scheduled for radioactive iodine ablation (RAI) therapy.

Optimization of instant sweet osmanthus white tea: formulation, sensory evaluation, and antioxidant properties.

Objective: This study aims to optimize the formulation of instant sweet osmanthus white tea (IOWT) and evaluate its antioxidant activities through assays.

Methods: Single-factor and orthogonal experiments were conducted to investigate the impacts of sweet osmanthus-to-white tea ratio and the concentrations of -cyclodextrin, erythritol, and citric acid on sensory properties and total flavonoids content (TFC) of IOWT. Mixtures of the dried ingredients were spray-dried to produce IOWT.

Inhaled alone versus inhaled plus intravenous polymyxin B for the treatment of pneumonia due to carbapenem-resistant gram-negative bacteria: A prospective randomized controlled trial.

Objectives: Infections due to carbapenem-resistant Gram-negative bacteria (CR-GNB) are associated with considerable morbidity and mortality. Polymyxin B (PMB) is a first-line agent for CR-GNB-associated pneumonia, but limited data exist on the clinical use of inhaled (IH) PMB.

Methods: A single-center, prospective randomized controlled trial was conducted in China to compare IH PMB alone with IH plus intravenous (IV) PMB between February 2022 and February 2024.

Socioeconomic status moderates the relationship between self-esteem and attitudes towards conspicuous consumption: An electrophysiological study.

Research on the impact of self-esteem on conspicuous consumption has shown inconsistent results. This study addresses this variability by examining how socioeconomic status (SES) moderates the relationship between self-esteem and conspicuous consumption. We hypothesized that the relationship varies with SES, predicting a positive relationship at high SES levels and a negative relationship at low SES levels.

The Effect of Induced Regulatory Focus on Frontal Cortical Activity.

The motivation-direction model has served as the primary framework for understanding frontal cortical activity. However, research on the link between approach/avoidance motivation and left/right frontal cortical activity has produced inconsistent findings. Recent studies suggest that regulatory systems may offer a more accurate explanation than the motivational direction model.

Case report and literature review: A thyroid storm patient with severe acute hepatic failure treated by therapeutic plasma exchange and a double plasma molecular absorption system.

Thyroid storm (TS) leading to acute liver failure is rare but fatal in clinical practice and hepatic failure can remarkably limit medication options for TS. We successfully cured a patient with TS complicated with acute hepatic failure using therapeutic plasma exchange (TPE) and a double plasma molecular absorption system (DPMAS) and summarized the case characteristics of 10 similar critical patients reported worldwide. We recommend that patients with TS complicated with liver failure disuse propylthiouracil or methimazole.

Extracellular vesicles ameliorates sleep deprivation induced anxiety-like behavior and cognitive impairment in mice.

The aim of this research was to explore the therapeutic capabilities of extracellular vesicles (EVs) derived from human umbilical cord mesenchymal stem cells (hUC-MSCs) that had been subjected to heat shock pretreatment, in treating psychiatric disorders induced by sleep deprivation in mice. The EVs were isolated and characterized, while western blotting was utilized to assess the expression of exosomal markers and heat shock protein 70 (HSP70). To evaluate the impact of EV treatment on anxiety-like behavior and cognitive impairment in sleep-deprived (SD) mice, the open field test, plus maze test, and Y-maze task were conducted.

Adsorption and desorption characteristics of flavonoids from white tea using macroporous adsorption resin.

White tea contains the highest flavonoids compared to other teas. While there have been numerous studies on the components of different tea varieties, research explicitly focusing on the flavonoid content of white tea remains scarce, making the need for a good flavonoid purification process for white tea even more important. This study compared the adsorption and desorption performance of five types of macroporous resins: D101, HP20, HPD500, DM301, and AB-8.

Correction of a transcranial acoustic field using a transient ultrasound field visualization technique.

Ultrasound, due to its noninvasive nature, has the potential to enhance or suppress neural activity, making it highly promising for regulating intractable brain disorders. Precise ultrasound stimulation is crucial for improving the efficiency of neural modulation and studying its mechanisms. However, the presence of the skull can cause distortion in the ultrasound field, thereby affecting the accuracy of stimulation.

Hsp70 ameliorates sleep deprivation-induced anxiety-like behavior and cognitive impairment in mice.

Background: Many neurobehavioral processes, including psychomotor, cognitive, and affection are negatively impacted by sleep deprivation (SD), which may be harmful to a person's physical and mental health. Heat shock proteins (Hsps) have been demonstrated to play a protective role in a number of neurodegenerative diseases and are essential for maintaining intracellular protein homeostasis, but their roles in SD remain elusive.

Methods: A mouse SD model was constructed using a modified multi-platform water environment method.

Understanding Rumor Sharing Behavior During COVID-19: The Dominant Motivation and the Potential Consequences for Life Satisfaction.

During the COVID-19 pandemic, rumors were shared widely and quickly, leading to unfortunate consequences. To explore the dominant motivation underlying such rumor sharing behavior and the potential consequences for sharers' life satisfaction, two studies were conducted. Study 1 was based on representative popular rumors that circulated throughout Chinese society during the pandemic to examine the dominant motivation underlying rumor sharing behavior.

Nodakenetin Alleviates Inflammatory Pain Hypersensitivity by Suppressing NF-κB Signal Pathway.

Background: Inflammatory pain mediated by nuclear factor kappa-B (NF-κB) signal pathway has become an increasingly important clinical issue in the last decade. As a potent antioxidant, Nodakenetin has been shown to have a prominent inhibitory effect on inflammation. However, the therapeutic effects and underlying pharmacological mechanisms of Nodakenetin for inflammatory pain remain unclear.

Trust in government buffers the negative effect of rumor exposure on people's emotions.

Unlabelled: Although we are surrounded by various kinds of rumors during the coronavirus disease pandemic, little is known about their primary content, what effect they might have on our emotions, and the potential factors that may buffer their effect. Combining qualitative (study 1 extracted 1907 rumors from top rumor-refuting websites using the Python Web Crawler and conducted content analysis) and quantitative (study 2 conducted an online survey adopting a three-wave design,  = 444) research methods, the current study revealed that government-related rumors accounted for the largest proportion of rumors during the outbreak stage of the pandemic and were positively associated with the public's negative emotions. We also found that trust in government negatively moderated the relationship between government-related rumors and negative emotions.

Can't forget: disruption of the right prefrontal cortex impairs voluntary forgetting in a recognition test.

The causal influence of the dorsolateral prefrontal cortex (DLPFC) in voluntary forgetting remains unclear. Here, we employed repetitive transcranial magnetic stimulation (rTMS) over the right DLPFC to temporarily disrupt function of this brain region and examined its influence on an item-method directed forgetting (DF) task with both neutral and negative emotional memories. Participants were assigned to either an active or a sham rTMS group, in which we administered stimulation for 20 min before the DF task.

The Dynamics of Belief Updating in Human Cooperation: Findings from inter-brain ERP hyperscanning.

Generally, successful cooperation can only be established when the interacting persons believe that they would not be betrayed; this belief can be updated by observing the other persons' actual choices. Thus, the process of belief updating plays an important role in conditional cooperation. Using the Prisoner's Dilemma Game (PDG) with event-related potential (ERP) hyperscanning, this study investigated the dynamics of belief updating in a dyad.

Long non‑coding RNA DLX6‑AS1 promotes proliferation by acting as a ceRNA targeting miR‑199a in cervical cancer.

Emerging evidence has revealed significant roles for long noncoding RNA (lncRNA) in various biological processes, including cell proliferation, apoptosis and invasion. The lncRNA distal‑less homeobox 6 antisense 1 (DLX6‑AS1) has been reported to serve as a vital oncogene during tumorigenesis and progression. However, the expression levels and functional roles of DLX6‑AS1 in cervical cancer are not yet well understood.

Intracranial pressure responsiveness to positive end-expiratory pressure in different respiratory mechanics: a preliminary experimental study in pigs.

Background: Respiratory mechanics affects the effect of positive end-expiratory pressure (PEEP) on intracranial pressure (ICP). Respiratory mechanics of the lung and the chest wall was not differentiated in previous studies. In the present study, we investigated the influence of the following possible determinants of ICP responsiveness to PEEP: chest wall elastance (E), lung elastance (E), and baseline ICP.

Critical role of the right VLPFC in emotional regulation of social exclusion: a tDCS study.

There is abundant evidence suggesting that the right ventrolateral prefrontal cortex (rVLPFC) plays an important role in down-regulating the emotional response to social exclusion. However, a causal relationship between rVLPFC function and explicit emotional regulation is not clear in the context of social exclusion. This study employed anodal transcranial direct current stimulation (tDCS) to activate rVLPFC while participants used emotional regulation to reappraise pictures of social exclusion.

Circulating microRNAs as a novel class of diagnostic biomarkers in gastrointestinal tumors detection: a meta-analysis based on 42 articles.

Objective: MicroRNAs (miRNAs) have become the focus of most recent efforts in cancer research. However, there have been inconsistencies in the literature regarding the suitability of circulating miRNAs for early detection of gastrointestinal cancers. This study aims to assess the diagnostic performance of circulating miRNAs in detection of gastrointestinal cancer through a meta-analysis.