Cross-Scale Synergy in MOF-Derived Catalysts: Bonded Fe-Co Atom Pairs with Oxygen Ligands Unlocking Enhanced Oxygen Reduction via d-Orbital Modulation.

Integrating cross-scale active sites-single atoms (SA), atom pairs (AP), and nanoparticles-into a unified catalytic system presents a promising strategy for advancing oxygen reduction reaction (ORR), an extremely important process in energy conversion. However, the synergistic interplay among these sites and their mechanistic roles remains poorly understood. Here, we report a novel catalyst (3) featuring Zn, bonded Fe-Co with dual-oxygen ligands, and FeCo nanoparticles, synthesized via pyrolysis of a metal matrix-engineered metal-organic framework (MOF).

Efficient Copper Biosorption by sp. ZC255: Strain Characterization, Kinetic-Equilibrium Analysis, and Genomic Perspectives.

Heavy metal pollution, particularly copper contamination, threatens the ecological environment and human survival. In response to this pressing environmental issue, the development of innovative remediation strategies has become imperative. Bioremediation technology is characterized by remarkable advantages, including its ecological friendliness, cost-effectiveness, and operational efficiency.

Short-range charge transfer for efficient ultra-narrowband deep blue afterglow.

Efficient and narrowband blue organic afterglow materials are critical components for advanced optoelectronic applications, but so far, have been rarely explored. Herein, we report short-range charge transfer-assisted high efficiency and ultra-narrowband deep blue (<450 nm) afterglow from a series of indolocarbazole-based chromophores. The short-range charge transfer within the fused π-conjugated frameworks enlarges the singlet-triplet energy gap and suppresses vibronic coupling and structural relaxations, thus leading to a slow reverse intersystem crossing rate, a long delayed-fluorescence lifetime of up to 186.

Efficacy and safety of serplulimab in solid tumors: a meta-analysis.

Objective: The goal of this study was to investigate the effectiveness and safety of serplulimab in advanced solid tumors through a meta-analysis approach.

Methods: An electronic search was conducted across the Embase, Web of Science, PubMed, and Cochrane Library databases, covering the period from each database's inception through 6 May 2025. Meta-analysis and related analyses, including subgroup, sensitivity, and publication bias assessments, were performed using Stata 16.

Sulfide promotes nitrogen removal in anammox low-strength ammonium wastewater treatment system.

Anammox has been widely used for denitrification from different wastewaters due to its low energy and carbon sources consumption. Nevertheless, the presence of nitrate in the effluent has been found to impede the enhancement of total nitrogen removal efficiency (TNRE). In this study, anammox was employed in conjunction with sulfur autotrophic denitrification (SAD) in order to enhance TNRE.

Recent advances in the treatment of gout with NLRP3 inflammasome inhibitors.

Gout is an autoinflammatory disorder characterized by the accumulation of monosodium urate crystals in joints and other tissues, representing the predominant type of inflammatory arthritis with a notable prevalence and propensity for severe outcomes. The NLRP3 inflammasome, a member of the pyrin domain-containing NOD-like receptor family, exerts a substantial impact on both innate and adaptive immune responses and serves as a pivotal factor in the pathogenesis of gout. In recent years, there has been significant academic and industrial interest in the development of NLRP3-targeted small molecule inhibitors as a promising therapeutic approach for gout.

Online Privacy-Preserving EEG Classification by Source-Free Transfer Learning.

Electroencephalogram (EEG) signals play an important role in brain-computer interface (BCI) applications. Recent studies have utilized transfer learning to assist the learning task in the new subject, i.e.

The resistance of hydrogenotrophic methanogenic microorganisms to ofloxacin in sludge anaerobic digestion process.

Ofloxacin (OFL) is a commonly used antibiotic that can enter wastewater treatment plants and be adsorbed by the sludge, resulting in a high OFL concentration in sludge and affecting the subsequent sludge anaerobic digestion process. However, the micro mechanisms involved in this process have not been thoroughly studied. Therefore, this study focuses on the effect of OFL on the sludge anaerobic digestion of sludge to provide such support.

Systemic regulation of binding sites in porous coordination polymers for ethylene purification from ternary C2 hydrocarbons.

The global demand for poly-grade ethylene (CH) is increasing annually. However, the energy-saving purification of this gas remains a major challenge due to the similarity in molecular properties among the ternary C2 hydrocarbons. To address this challenge, we report an approach of systematic tuning of the pore environment with organic sites (from -COOH to -CF, then to -CH) in porous coordination polymers (PCPs), of which NTU-73-CH shows remarkable capability for the direct production of poly-grade CH from ternary C2 hydrocarbons under ambient conditions.

Solvents regulate the packing porosity of a bilayer metal-organic cage.

Metal-organic cages (MOCs) are an emerging class of porous materials with promising applications. However, controlling the configuration of the cage packing, which can influence the overall porosity of the materials, remains a difficulty, as many factors can influence the cage assembly and stacking. Herein, we report a solvent strategy to fine-tune the packing configuration of a bilayer MOC, a small triangular prism cage (six Cu ions act as vertices, three nitrate ions act as pillars, and six nitrate ions act as caps) incorporated into a large triangular prism cage (another six Cu ions act as vertices, a couple of oxygen atoms act as pillars and six ligands (L1: 3,5-bis(pyridine-3-yl)-4-1,2,4-triazole) act as a jointed cap) by the coordination between the triazole nitrogen from L1 and the inner vertex Cu ions.

A Light-Triggered J-Aggregation-Regulated Therapy Conversion: from Photodynamic/Photothermal Therapy to Long-Lasting Chemodynamic Therapy for Effective Tumor Ablation.

Reactive oxygen species (ROS) have become an effective tool for tumor treatment. The combination of photodynamic therapy (PDT) and chemodynamic therapy (CDT) takes advantage of various ROS and enhances therapeutic effects. However, the activation of CDT usually occurs before PDT, which hinders the sustained maintenance of hydroxyl radicals (⋅OH) and reduces the treatment efficiency.

Chinese expert consensus on the diagnosis, treatment, and management of asthma in women across life.

Background: The epidemiology and severity of asthma vary by sex and age. The diagnosis, treatment, and management of asthma in female patients are quite challenging. However, there is hitherto no comprehensive and standardized guidance for female patients with asthma.

A novel minimally invasive fixation method for flail chest management in a Canine model: an animal research.

Background: Multiple rib fractures can lead to flail chest with up to 35% mortality rate due to severe pulmonary complications. Current treatments of flail chest remain controversial. Studies have shown that surgical treatments can improve outcomes and reduce mortality, comparing to non-operative treatments.

Synergistic Catalysis of Cobalt Tetroxide and Bamboo-Shaped Carbon Nanotubes Doped with Nitrogen for Oxygen Reduction in Zn-Air Batteries.

Zinc-air batteries (ZABs) have been considered as one of the most emerging systems for energy conversion and storage. However, the preparation of highly efficient oxygen reduction reaction (ORR) catalysts on an air cathode is still faced with significant challenges. Herein, we report a secondary nitrogen source strategy for fine-tuning the active center, which provides a carbon-based hierarchical porous catalyst (termed CoO@N/CNT-1000) for highly efficient ORR activity ( = 0.

The role of crystallinity of palladium nanocrystals in ROS generation and cytotoxicity induction.

Palladium (Pd) nanocrystals with different crystalline forms exhibit distinct enzyme-like activities in generating reactive oxygen species (ROS). How such crystallinity-dependent catalytic activity regulates potential cytotoxicity remains to be elucidated. In the present work, Pd nanocrystals with four different crystalline forms were synthesized, and the underlying mechanisms involved in ROS-mediated cytotoxicity were systematically revealed.

Sequential exposures of single walled carbon nanotubes and heavy metal ions to macrophages induce different cytotoxicity.

The probability of occupational exposure rises with the increasing production and biomedical application of carbon nanotubes (CNTs). Thus, the risk of co-exposure of nanomaterials with environmental pollutants is also increasing. Although many studies have focused on the combined toxicity of nanomaterials and pollutants, more attention has been paid to the toxicity of nanomaterials after adsorbing pollutants or the toxicity of nanomaterials and pollutants exposed simultaneously.

Positive feedback on dewaterability of waste-activated sludge by the conditioning process of Fe(II) catalyzing urea hydrogen peroxide.

The treatment and disposal of sludge is a complex environmental problem because of the high moisture content. Herein, We reported the process of Fe(II) activating Urea hydrogen peroxide (UHP) to improve waste activated sludge (WAS) dewaterability for the first time. Fe(II)/UHP was proven to significantly improve WAS dewaterability.

A heptamethine cyanine with -induced rearrangement for acid-activated tumour imaging and photothermal therapy.

Photothermal therapy has been developed as one of the most attractive strategies for tumour therapy. However, most of the reported photothermal probes still suffer from poor selectivity or specificity for the tumour region during treatment. Herein, a tumour acidic microenvironment activated heptamethine cyanine-based nanoprobe (Cy-TPA NPs) is constructed for fluorescence imaging-guided photothermal therapy with enhanced tumour specificity.

Mitigation of Obesity-Related Systemic Low-Grade Inflammation and Gut Microbial Dysbiosis in Mice with Nanosilver Supplement.

Systemic low-grade inflammation and imbalance of gut microbiota are important risk factors promoting the progression of obesity-related metabolic disorders. This provides potential pharmacological and nutritional targets for the management of obesity and obesity-related disorders. Here, we evaluated the modulatory effects of nanosilver on obesity-related systemic low-grade inflammation and gut microbial dysbiosis.

The degradation of allyl isothiocyanate and its impact on methane production from anaerobic co-digestion of kitchen waste and waste activated sludge.

Producing methane from anaerobic co-digestion of kitchen waste and waste activated sludge has been widely implemented in real-world situations. However, the fate and impact of allyl isothiocyanate (AITC), a main active component in cruciferous vegetables, in the anaerobic co-digestion has never been documented. This study therefore aims to provide such supports.

Insights into how poly aluminum chloride and poly ferric sulfate affect methane production from anaerobic digestion of waste activated sludge.

Poly aluminum chloride (PAC) and poly ferric sulfate (PFS) are widely used in wastewater treatment and sludge dewatering, resulting in their amounts being accumulated substantially in waste activated sludge (WAS). Till now, however, little information about their influence on WAS digestion is available. This work therefore aims to provide insights into how PAC and PFS affect sludge anaerobic digestion.

Electrostatic attraction of cationic pollutants by microplastics reduces their joint cytotoxicity.

Microplastic (MP) pollution causes global concerns regarding the consequential impacts on human health. In particular, MPs may act as vectors for various contaminants to induce adverse effects in human. In this work, the joint cytotoxicity of two different MPs co-exposed with diverse ionic pollutants was investigated in two cell lines from human digestive system: human gastric epithelium (GES-1) and colorectal mucosa (FHC) cell lines.

Effect of sodium dodecylbenzene sulfonate on hydrogen production from dark fermentation of waste activated sludge.

Sodium dodecylbenzene sulfonate (SDBS), a typical surfactant being widely used in various applications, was highly accumulated in waste activated sludge. To date, however, its effect on hydrogen production from dark fermentation of sludge has not been documented. The work therefore aimed to explore whether and how SDBS affects hydrogen production.

Health-related quality of life in different trimesters during pregnancy.

Background: Pregnant women experience physical, physiological, and mental changes. Health-related quality of life (HRQoL) is a relevant indicator of psychological and physical behaviours, changing over the course of pregnancy. This study aims to assess HRQoL of pregnant women during different stages of pregnancy.

Per- and polyfluoroalkyl substances exposure during pregnancy and adverse pregnancy and birth outcomes: A systematic review and meta-analysis.

Background: Exposure to per- and polyfluoroalkyl substances (PFAS) during pregnancy has been suggested to be associated with adverse pregnancy and birth outcomes; however, the findings have been inconsistent. We aimed to conduct a systematic review and meta-analysis to provide an overview of these associations.

Methods: The online databases PubMed, EMBASE and Web of Science were searched comprehensively for eligible studies from inception to February 2021.