Accuracy Bias and Factors Influencing Polysomnography and Consumer Sleep-Monitoring Device Measuring of Total Sleep Time: A Mixed-Methods Study.

Objective: The Huawei Band 9 (HWB 9), a consumer sleep-monitoring device with a high market share and a large user base in China, can provide sleep staging parameters and has broad representativeness in sleep monitoring applications. This study aims to compare the accuracy bias of polysomnography (PSG) and consumer sleep-monitoring devices, specifically the HWB 9, in measuring total sleep time (TST) and explore the factors affecting accuracy bias.

Methods: This study employed a sequential explanatory mixed-methods design, with quantitative research comprising 108 samples and qualitative research comprising 18 samples.

PCSK9 is upregulated and correlated with more severe disease condition but fails to predict treatment outcomes in psoriasis patients.

Background: Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) not only regulates cholesterol metabolism and cardiovascular disorder but also modifies inflammatory response and autoimmunity.

Objective: This study investigated the relation of PCSK9 to clinical features and treatment outcomes in psoriasis patients.

Methods: One hundred and five psoriasis patients who initiated systemic treatment due to moderate-to-severe disease condition were enrolled.

Medication safety analysis of elderly inpatients based on improved functional resonance analysis method (FRAM): a mixed methods study.

The study aimed to quantitatively assess functional risks in the medication administration process of elderly inpatients and develop management measures from a holistic system safety perspective. The functional resonance analysis method and decision-making trial and evaluation laboratory (DEMATEL) method were introduced to graphically model the medication administration process in elderly inpatients and identify safety issues affecting the complex interactions of functions. Semi-structured interviews based on the Fit between Individual, task, technology, and environment framework were used to explore medication safety management measures.

A Cross-Sectional Study of the Practice of Orthopedic Specialty Nursing in Hospitals in Jiangsu Province.

Purpose: To evaluate the development status of orthopedic specialty nursing in hospitals in Jiangsu Province in China.

Patients And Methods: This cross-sectional study was conducted from August to September 2024 in the orthopedics departments of secondary and tertiary hospitals in Jiangsu Province, China. Data were collected using a self-designed questionnaire administered through the online platform Wenjuan Xing.

Efficacy and safety of coenzyme Q10 in heart failure: a meta-analysis of randomized controlled trials.

Background: The effectiveness and adverse effects of coenzyme Q10 for heart failure remain unclear owing to small sample sizes and variations in the quality of existing studies in literature.

Methods: The databases of EMBASE, PubMed, Web of Science, CINAHL databases, Scopus, Cochrane Central Register of Controlled Trials, VIP, Wanfang, and CNKI were searched for randomized controlled trials on the coenzyme Q10-assisted treatment of heart failure. Relevant literature was retrieved, data were extracted, and the risk of bias of the included studies was evaluated by two investigators independently using the Review Manager 5.

The role of serum inflammatory factors in predicting treatment response in patients with vitiligo and concomitant Hashimoto's thyroiditis.

Introduction: Vitiligo (VL) is associated with several autoimmune diseases, especially Hashimoto's thyroiditis, VL and concomitant Hashimoto's thyroiditis (HT) up to 34% in VL.

Aim: To assess the predictive value of serum inflammatory factors in guiding treatment response among patients with concurrent VL and concomitant HT.

Material And Methods: This retrospective study enrolled 67 cases of VL and concomitant HT, and the patients according to treatment outcomes were divided into the unsatisfied group and the satisfied group.

Effect of peer support interventions in patients with type 2 diabetes: A systematic review.

Objective: This study aims to assess the effectiveness of a peer support intervention on the quality of life (QOL), self-management, self-efficacy, glycated hemoglobin (HbA1c), and depression in patients with type 2 diabetes mellitus (T2DM).

Methods: A systematic review was conducted by searching 10 databases, namely PubMed, The Cochrane Library, Embase, Medline, CINHAL, Web of Science, Sinomed, CNKI, WanFang Data, and VIP for articles published from January 1974 to April 2023.

Results: A total of 12 studies were included.

Evaluation of Therapeutic Effect and Prognosis of Danzhi Xiaoyao Powder Combined with Photodynamic Therapy in the Treatment of Rose Acne.

Background: Rose acne is a chronic inflammatory skin disease that can cause paroxysmal flushing, persistent erythema, papules or papules on the face, and pustules, and it has a greater impact on the life of patients, so it is important to treat it.

Objective: To investigate the effect of Danzhi Xiaoyao Powder combined with photodynamic therapy (PDT) on the curative effect evaluation and prognosis of patients with rose acne. .

MiR-338-5p promotes the growth and metastasis of malignant melanoma cells via targeting CD82.

Background: Melanoma has been a severe threat to human health, microRNAs play vital roles in the oncogenesis and progression of cancers. In this report, the roles and mechanism of miR-338-5p were investigated in the development of melanoma.

Materials And Methods: A total of 46 melanoma samples and 25 normal nevi samples were collected.

miR‑367 enhances the proliferation and invasion of cutaneous malignant melanoma by regulating phosphatase and tensin homolog expression.

Melanoma presents a serious threat to human health but the underlying mechanisms have not been fully identified. Increasing evidence indicates that microRNAs exert a significant influence on the tumorigenesis and metastasis of different types of cancer. The present study aimed to identify the role of microRNA (miR)‑367 in the initiation and progression of melanoma and investigate its potential target.