Cu-doped ZnO nanozyme with citric acid modification alleviate saline-alkaline stress in wheat by scavenging reactive oxygen species.

Saline-alkaline stress severely impedes plant growth and productivity. One of the main consequences of this stress is the excessive accumulation of reactive oxygen species (ROS), leading to cellular oxidative damage. Therefore, developing effective strategies for rapidly and efficiently removing ROS is crucial for improving plant tolerance to saline conditions.

Machine learning-assisted triple-emission Ln-MOFs sensor array for detection of multiple PFCs in aqueous environments.

Perfluorinated compounds (PFCs) are persistent environmental pollutants with potential carcinogenicity, posing a major threat to ecosystems and human health. Rapid identification of PFCs in complex environmental matrices remains challenging due to the limitations of conventional single-emission probes in their sensitivity to environmental disturbances. This study developed a three-channel fluorescence sensing platform based on a europium/terbium (Eu/Tb) bimetallic organic framework.

Sevoflurane: A dual modulator of miR‑211‑5p and mitochondrial apoptosis in glioma therapy.

The present study aimed to investigate how sevoflurane (SEV) regulated the apoptosis of glioma cells through the mitochondrial apoptosis pathway. First, an evaluation was performed on the viability, apoptosis, mitochondrial reactive oxygen species levels, mitochondrial membrane potential and apoptosis and autophagy‑related protein expression of glioma cells according to experimental groups. Next, the expression of microRNA‑211‑5p (miR‑211‑5p), silent information regulator 1 (SIRT1) and phosphatidylinositol 3‑kinase (PI3K)/protein kinase B (AKT) signaling pathway was detected by reverse transcription‑quantitative PCR or western blotting.

PpBOR1 is critical for the excess borate tolerance of Physcomitrium patens.

Functional analysis of BORs in Physcomitrium patens indicates that both PpBOR1 and PpBOR2 possess boron efflux transporter activity, and PpBOR1 is essential for the plant's tolerance to excessive boron stress. Boron (B), an essential plant micronutrient, is crucial for achieving optimal agricultural yield. Although the function of the BOR family proteins as borate efflux transporters has been established in tracheophytes, the role of their counterparts in non-vascular plants has not been thoroughly investigated.

"Light-Up" Near-Infrared Fluorescent Probe for Visualization of Hydrogen Sulfide Content and Abiotic Stress Response in Plants.

Hydrogen sulfide (HS) plays a vital role in plant physiology and stress adaptation, but the detection of endogenous HS remains a challenge. In this work, a near-infrared fluorescent probe (NIR-BOD-HS) was synthesized using boron-dipyrromethene (BODIPY) as the raw material, which showed a good linear relationship in the concentration range of 0.1-70 μM and a detection limit of 56 nM.

Combination of serum ACSL4 levels and low-dose 256-slice spiral CT exhibits the potential in the early screening of lung cancer.

Background: The prognosis of lung cancer is related to the stage of the disease at the time of detection, and early diagnosis can prolong survival time. In this prospective observational cohort research, we aimed to analyze the diagnostic performance of the combined application of ACSL4 and low-dose 256-slice spiral computed tomography (CT) to lung cancer.

Methods: This prospective observational cohort research enrolled a total of 512 patients with pulmonary nodules (PN) who were found with PN by CT.

A rare rectal gastrointestinal stromal tumor with indolent biological behavior: A case study.

The overall incidence of rectal gastrointestinal stromal tumor (RGIST) has risen, but it remains a rare disease. Furthermore, tumor rupture is associated with poor prognosis. The present study reported a rare case of RGIST with indolent biological behavior.

Positive therapy outcome of lung squamous cell cancer: A case report.

Lung cancer is a rapidly progressing disease with a poor prognosis. Lung squamous cell cancer (LSCC) accounts for 20-30% of lung cancer cases. Conventional chemotherapy and radiotherapy are the common options for LSCC.

Coix seed oil regulates mitochondrial functional damage to induce apoptosis of human pancreatic cancer cells via the PTEN/PI3K/AKT signaling pathway.

Background: Coix seed oil (CSO) has a wide range of anticancer effects. However, the mechanism of action against pancreatic cancer (PC) and regulation of mitochondria in vitro is still unclear.

Materials And Results: This research investigated the possible mechanism of CSO induction of PC cell apoptosis and regulating mitochondrial functional damage.

Quantitative Evaluation of Small Intestinal Hemorrhage Using Energy Spectrum CT Iodine-Water Map.

The objective of this research is to analyze the quantitative evaluation of human small intestinal bleeding by observing and analyzing animal experiments of small intestinal hemorrhage in rabbit models for the convenience of understanding the role of energy spectrum CT iodine-water diagram in animal experimental research of quantitative evaluation of small intestinal bleeding in rabbit models. Compared with the energy spectrum of iodine-water graph of a rabbit CT model, the present study studied the quantitative evaluation of small intestinal bleeding by using a rabbit model instead of human. According to the method mentioned above and the analysis of experimental data, the role of energy spectrum CT iodine-water map and the quantitative evaluation of human small intestinal bleeding have been understood.

Loss of Happiness for Land-Expropriated, Urbanised Residents: A Comparison Based on Multiple Groups.

Are land-expropriated, urbanised residents living happily? This question is not only related to the quality of urbanisation but also has important reference for evaluating the reform of the land acquisition system. On the basis of the Chinese General Social Survey data in 2017 and 2018, the HeckProbit model, the ordered probit model and the mediating effect model were used to study the happiness and underlying mechanism of land-expropriated, urbanised residents. The results showed that the older the farmers are, the lower the probability of obtaining urban hukou through land acquisition, and women will be more likely to achieve household registration through land requisition.

Vitamin intake and pancreatic cancer risk reduction: A meta-analysis of observational studies.

Background: The relationship between vitamin intake and pancreatic cancer (PC) risk is disputed. We aimed to investigate the association between vitamin intake and the risk of PC via meta-analysis.

Methods: We conducted a meta-analysis of studies concerning vitamin intake and the risk of PC from EMBASE, MEDLINE, and Cochrane Library.