Correction: Characteristics and correlations of sleep disorders in patients with relapsing-remitting multiple sclerosis in China: a cross-sectional study.

[This corrects the article DOI: 10.3389/fneur.2025.

Characteristics and correlations of sleep disorders in patients with relapsing-remitting multiple sclerosis in China: a cross-sectional study.

Background: Sleep disorders are a major but overlooked symptom in patients with multiple sclerosis (MS).

Objectives: This article aims to investigate the characteristics of sleep disorders in patients with relapsing-remitting multiple sclerosis (RRMS) and to analyze the correlations between sleep disorders in RRMS and anxiety, depression, fatigue, and cognitive impairment.

Methods: A total of 35 patients with RRMS and 35 controls were included, and both groups underwent assessments for sleep, anxiety, depression, fatigue, and cognitive function.

Research progress in sleep disorders associated with multiple sclerosis.

Multiple sclerosis is a common demyelinating disease in neurology, characterized by a complex and unpredictable pathogenesis, as well as diverse clinical manifestations, which impose a significant burden on the physical and mental health of patients. Sleep disturbances, as a prevalent yet often overlooked disabling symptom in this disease, have a high incidence rate and significantly reduce the quality of life for patients. This article systematically reviews recent advancements in sleep disorders associated with multiple sclerosis (MS), analyzing their epidemiological patterns, underlying pathophysiology, and management strategies for five core manifestations: insomnia, sleep-disordered breathing, restless legs syndrome, narcolepsy, and circadian rhythm dysregulation.

Fatigue and its correlation with anxiety and depression in patients with multiple sclerosis in China.

Background: Multiple Sclerosis (MS) is a chronic, progressive, immune-mediated disease of the central nervous system. Fatigue is a common and disabling symptom in patients with MS (PwMS). Some psychological factors, such as depression, stress, and anxiety, also appear to be related to these issues.

Environmental uncertainty, supply chain, and stability of sustainable green innovation:Based on micro evidence from energy-intensive enterprises.

In the context of the low-carbon transformation of energy-intensive enterprises, the stability risks of continuous green innovation and their transmission mechanisms within the supply chain warrant attention. Specifically, will these stability risks be transmitted along the supply chain? If so, how are they transmitted? Therefore, this study focuses on Chinese energy-intensive enterprises and their upstream and downstream companies from 2008 to 2021. It explores the transmission effects of stability risks of continuous green innovation within the supply chain and the role of environmental uncertainty.

Intelligent transformation, fintech, and green Growth：A general equilibrium analysis based on credit allocation perspective.

This paper conducted an in-depth study to elucidate the impact of corporate intelligence transformation and regional financial technology on green economic growth, particularly the role of credit resource allocation. We developed a multi-sector general equilibrium model, integrating the heterogeneity of intelligent transformation in production sectors and accounting for the influence of Fintech on financial institutions. Within this model framework, panel data from 2011 to 2021 at the provincial, municipal, and micro-enterprise levels in China were used to validate the theoretical model through a mixed regression approach.

Phase 1 study of safety and preliminary efficacy of intranasal transplantation of human neural stem cells (ANGE-S003) in Parkinson's disease.

Background: Intranasal transplantation of ANGE-S003 human neural stem cells showed therapeutic effects and were safe in preclinical models of Parkinson's disease (PD). We investigated the safety and tolerability of this treatment in patients with PD and whether these effects would be apparent in a clinical trial.

Methods: This was a 12-month, single-centre, open-label, dose-escalation phase 1 study of 18 patients with advanced PD assigned to four-time intranasal transplantation of 1 of 3 doses: 1.

Efficacy of levetiracetam combined with oxcarbazepine in the treatment of adults with temporal lobe epilepsy and its impact on memory and cognitive function.

Objective: To explore the effect of levetiracetam combined with oxcarbazepine on the memory and cognitive function of adult patients with temporal lobe epilepsy.

Methods: This retrospective analysis included 91 adult patients with temporal lobe epilepsy treated at Xianyang Hospital from June 2020 to December 2022. Based on their medication regimen, patients were categorized into an observation group (n=51) receiving levetiracetam plus oxcarbazepine and a control group (n=40) receiving only levetiracetam.

New evidence on the real role of digital economy in influencing public health efficiency.

In recent years, the rapid advancement of digital technology has supported the growth of the digital economy. The transformation towards digitization in the public health sector serves as a key indicator of this economic shift. Understanding how the digital economy continuously improves the efficiency of public health services and its various pathways of influence has become increasingly important.

Mild hypothermia promotes neuronal differentiation of human neural stem cells via RBM3-SOX11 signaling pathway.

Both therapeutic hypothermia and neural stem cells (NSCs) transplantation have shown promise in neuroprotection and neural repair after brain injury. However, the effects of therapeutic hypothermia on neuronal differentiation of NSCs are not elucidated. In this study, we aimed to investigate whether mild hypothermia promoted neuronal differentiation in cultured and transplanted human NSCs (hNSCs).

Transplantation of human neural stem cell prevents symptomatic motor behavior disability in a rat model of Parkinson's disease.

Parkinson's disease (PD) is a ubiquitous brain cell degeneration disease and presents a significant therapeutic challenge. By injecting 6-hydroxydopamine (6-OHDA) into the left medial forebrain bundle, rats were made to exhibit PD-like symptoms and treated by intranasal administration of a low-dose (2 × 10) or high-dose (1 × 10) human neural stem cells (hNSCs). Apomorphine-induced rotation test, stepping test, and open field test were implemented to evaluate the motor behavior and high-performance liquid chromatography was carried out to detect dopamine (DA), 3,4-dihydroxyphenylacetic acid (DOPAC), serotonin, and 5-hydroxyindole-3-acetic acid in the striatum of rats.

Effect of Sasobit/Waste Cooking Oil Composite on the Physical, Rheological, and Aging Properties of Styrene-Butadiene Rubber (SBR)-Modified Bitumen Binders.

The modifying effects of polymer on bitumen low-temperature performance are substantially compromised by the thermal breakdown of styrene-butadiene rubber (SBR) polymer during bitumen mixture production operations. The efficacy of the utilization of Sasobit/waste cooking oil (Sasobit/WCO) as a warm-mix additive has been demonstrated in mitigating the adverse consequences of thermal aging on SBR-modified bitumen binder (SB) while preserving the binder's original performance characteristics. However, few studies have been conducted to further investigate the rheological properties and aging resistance of SB modified with Sasobit/WCO compounds.

Towards sustainability: the impact of industrial synergistic agglomeration on the efficiency of regional green development.

Guided by the concept related to sustainable development, we investigate the effects related to the synergistic agglomeration development of productive service and manufacturing industries on regional green development, which is also an important path for promoting the global sustainable development process and achieving carbon neutrality goals. Using the panel data of 285 prefecture-level cities in China from 2011 to 2020 as the basis of our study, we focus on the impact of industrial synergistic agglomeration on the efficiency of regional green development and the mediating influence of technological innovation. Results show that (1) industrial synergistic agglomeration positively contributes to the improvement of regional green development efficiency level and is significantly positive at the 5% level, (2) technological innovation plays a mediating role in the process of promoting regional green development efficiency through industrial synergistic agglomeration and can better realise the green development effect of industrial synergistic agglomeration, (3) results of the threshold effect test show the nonlinear effect of industrial synergistic agglomeration on regional green development efficiency with a single threshold value of 3.

Green credit and enterprise green operation: Based on the perspective of enterprise green transformation.

This paper uses panel data of listed heavily polluting enterprises from 2007 to 2021, based on the perspective of transformation and upgrading of heavy polluters, innovatively studies the impact of green credit on the green operation of enterprises. At the micro level, the research results of this paper verify the effectiveness of green credit policy on the transformation of green enterprises. It is also found that the two intermediary paths of debt cost and government subsidy play a partial intermediary role in the process of green credit promoting green enterprise transformation and upgrading.

General Method for Pesticide Recognition Using Albumin-Based Host-Guest Ensembles.

The massive use of pesticides nowadays has led to serious consequences for the environment and public health. Fluorescence analytical methods for pesticides are particularly advantageous with respect to simplicity and portability; however, currently available fluorescence methods (enzyme-based assays and indicator displacement assays) with poor universality are only able to detect few specific pesticides (., organophosphorus).

A surfactant-assisted approach enables the fluorescence tracking of benfluralin in plants.

Developing an effective detection method for benfluralin (BFA) is of great significance, since BFA as most widely used herbicides can be bioaccumulated by aquatic organisms in environment, possessing potential risks to human health. Owing to aggregation-caused quenching effect, most fluorescent detection methods based on donor-acceptor organic fluorophores suffered from very low sensitivity towards BFA in water system, hampering the bioimaging application in plants. In this work, we reported a novel surfactant-assisted fluorescent probe enabling detection of BFA in water with a high sensitivity.

Brain Extract of Subacute Traumatic Brain Injury Promotes the Neuronal Differentiation of Human Neural Stem Cells via Autophagy.

Background: After a traumatic brain injury (TBI), the cell environment is dramatically changed, which has various influences on grafted neural stem cells (NSCs). At present, these influences on NSCs have not been fully elucidated, which hinders the finding of an optimal timepoint for NSC transplantation.

Methods: Brain extracts of TBI mice were used in vitro to simulate the different phase TBI influences on the differentiation of human NSCs.

A near-infrared dicyanoisophorone-based fluorescent probe for discriminating HSA from BSA.

Despite the rapid development of fluorescent probe techniques for the detection of human serum albumin (HSA), a probe that discriminates between HSA and bovine serum albumin (BSA) is still a challenging task, since their similar chemical structures. As a continuation of our work, herein, a dicyanoisophorone-based fluorescent probe DCO2 is systematically studied for discrimination of HSA from BSA. The photophysical and sensing performances of DCO2, including basic spectroscopic properties, sensing sensitivity, and selectivity, exhibits that DCO2 could selectively bind with HSA and display remarkable fluorescence enhancement (∼254-fold) at 685 nm.

Modulating donor of dicyanoisophorone-based fluorophores to detect human serum albumin with NIR fluorescence.

It is urgently needed to develop NIR-fluorescent probe for detection of human serum albumin (HSA) since the interference of short-wavelength-fluorescence from endogenous species in real serum and urine. However, most previous reports were located in the short-wavelength region (<600 nm). In this work, a series of dicyanoisophorone (DCO)-based fluorophores 1-4 with different donor groups have been designed and investigated.

JKAP, Th1 cells, and Th17 cells are dysregulated and inter-correlated, among them JKAP and Th17 cells relate to cognitive impairment progression in Alzheimer's disease patients.

Background: JNK pathway-associated phosphatase (JKAP) is engaged in Alzheimer's disease (AD) pathology via regulating immune response, cluster of differentiation 4 positive (CD4) T cell differentiation, inflammation, and phosphorylated tau (p-tau). This study aimed to investigate its clinical value serving as a biomarker for AD.

Methods: Fifty AD patients, 50 Parkinson's disease (PD) patients, and 50 controls (patients with non-degenerative neurological diseases with normal cognition) were enrolled.

A retrospective study on the preventive effect of statin after carotid artery stenting.

This retrospective study appraised the preventive effect of statin after carotid artery stenting (CAS).Records were extracted for 100 patients with CAS surgery indicator, aged between 20 and 75 years old, and treated for statin. The cohort study included treatment group (statin and routine treatment) and control group (routine treatment), each group 50 patients.

Fluorescence discrimination of HSA from BSA: A close look at the albumin-induced restricted intramolecular rotation of flavonoid probe.

Discrimination of human serum albumin (HSA) from bovine serum albumin (BSA) based on the fluorescence probe technique is still challenging due to similar chemical structures. In this work, a novel flavonoid-based fluorescent probe AF is reported for successful discrimination of HSA from BSA. The sensing performances of probe, including sensing dynamic, sensitivity and selectivity, have been carefully studied.